Deep vein thrombosis pathophysiology: Difference between revisions
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These are collectively known as [[Virchow's triad]]. | These are collectively known as [[Virchow's triad]]. | ||
More deep venous thrombosis occurred in the left leg than in the right and | More deep venous thrombosis occurred in the left leg than in the right and unerlying cause being the compression of the left common iliac vein by the overlying right common iliac artery.(see [[May-Thurner syndrome]]) | ||
It is recognized that thrombi usually develop first in the calf veins, "growing" in the direction of flow of the vein. DVTs are distinguished as being above or below the [[popliteal]] vein. Very extensive DVTs can extend into the [[iliac vein]]s or the [[inferior vena cava]]. The risk of pulmonary embolism is higher in the presence of more extensive clots. | It is recognized that thrombi usually develop first in the calf veins, "growing" in the direction of flow of the vein. DVTs are distinguished as being above or below the [[popliteal]] vein. Very extensive DVTs can extend into the [[iliac vein]]s or the [[inferior vena cava]]. The risk of pulmonary embolism is higher in the presence of more extensive clots. | ||
Revision as of 14:27, 26 August 2011
Editors-in-Chief: C. Michael Gibson, M.S., M.D. Associate Editor-In-Chief: Ujjwal Rastogi, MBBS [1]
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Pathophysiology
Rudolf Virchow noted several factors affecting the clot formation, which are:
- Alterations in blood flow (stasis)
- Injury to the vascular endothelium
- Alterations in the constitution of blood (hypercoagulability)
These are collectively known as Virchow's triad.
More deep venous thrombosis occurred in the left leg than in the right and unerlying cause being the compression of the left common iliac vein by the overlying right common iliac artery.(see May-Thurner syndrome)
It is recognized that thrombi usually develop first in the calf veins, "growing" in the direction of flow of the vein. DVTs are distinguished as being above or below the popliteal vein. Very extensive DVTs can extend into the iliac veins or the inferior vena cava. The risk of pulmonary embolism is higher in the presence of more extensive clots.