Patent foramen ovale and migraine: Difference between revisions
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==Patent foramen ovale and migraine== | ==Patent foramen ovale and migraine== | ||
A recent metanalysis including 18 studies and comprising 2636 patients, found a low-grade positive association between migraines in patients with [[patent foramen ovale]] ([[PFO]]) <ref name="pmid18355348">{{cite journal| author=Schwedt TJ, Demaerschalk BM, Dodick DW| title=Patent foramen ovale and migraine: a quantitative systematic review. | journal=Cephalalgia | year= 2008 | volume= 28 | issue= 5 | pages= 531-40 | pmid=18355348 | doi=10.1111/j.1468-2982.2008.01554.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18355348 }} </ref>. However, the results of this study should be interpreted with cautions, as the individual studies included for the metanalysis were quite heterogeneous. There was some positive association seen in patients of [[migraine]] with aura {odds ratio of 3.21(95% CI 2.38–4.70)} but no such relation was seen for patients of [[migraine]] without aura | A recent metanalysis including 18 studies and comprising 2636 patients, found a low-grade positive association between migraines in patients with [[patent foramen ovale]] ([[PFO]]) <ref name="pmid18355348">{{cite journal| author=Schwedt TJ, Demaerschalk BM, Dodick DW| title=Patent foramen ovale and migraine: a quantitative systematic review. | journal=Cephalalgia | year= 2008 | volume= 28 | issue= 5 | pages= 531-40 | pmid=18355348 | doi=10.1111/j.1468-2982.2008.01554.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18355348 }} </ref>. However, the results of this study should be interpreted with cautions, as the individual studies included for the metanalysis were quite heterogeneous. There was some positive association seen in patients of [[migraine]] with aura {odds ratio of 3.21(95% CI 2.38–4.70)} but no such relation was seen for patients of [[migraine]] without aura | ||
Another case control study done to evaluate the association between migraine headaches and [[patent foramen ovale]] ([[PFO]])found no significant association between the two. The prevalence of [[patent foramen ovale]] ([[PFO]]) was similar in case and control (26.4% versus 25.7%;P=0.90). Unlike the metanalysis discussed above, no difference in PFO prevalence was found in those with migraine with aura and those without (P=0.93). | |||
==References== | ==References== | ||
Revision as of 02:06, 7 September 2011
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [3]
Overview
Migraine headaches, particular those with an aura, have been associated with a patent foramen ovale.
Patent foramen ovale and migraine
A recent metanalysis including 18 studies and comprising 2636 patients, found a low-grade positive association between migraines in patients with patent foramen ovale (PFO) [1]. However, the results of this study should be interpreted with cautions, as the individual studies included for the metanalysis were quite heterogeneous. There was some positive association seen in patients of migraine with aura {odds ratio of 3.21(95% CI 2.38–4.70)} but no such relation was seen for patients of migraine without aura
Another case control study done to evaluate the association between migraine headaches and patent foramen ovale (PFO)found no significant association between the two. The prevalence of patent foramen ovale (PFO) was similar in case and control (26.4% versus 25.7%;P=0.90). Unlike the metanalysis discussed above, no difference in PFO prevalence was found in those with migraine with aura and those without (P=0.93).
References
- ↑ Schwedt TJ, Demaerschalk BM, Dodick DW (2008). "Patent foramen ovale and migraine: a quantitative systematic review". Cephalalgia. 28 (5): 531–40. doi:10.1111/j.1468-2982.2008.01554.x. PMID 18355348.