Arcus senilis: Difference between revisions
| Line 26: | Line 26: | ||
It can be a sign of disturbance in [[lipid]] metabolism, an indicator of conditions such as [[hypercholesterolemia]], [[hyperlipoproteinemia]] or [[hyperlipidemia]]. | It can be a sign of disturbance in [[lipid]] metabolism, an indicator of conditions such as [[hypercholesterolemia]], [[hyperlipoproteinemia]] or [[hyperlipidemia]]. | ||
==Natural History, Complications, Prognosis== | |||
===Association with Atherosclerosis=== | |||
In the past, arcus has been said to be associated with [[atherosclerosis]]. However, a prospective population based cohort study (The Copenhagen City Heart Study), in which a total of 12,745 participants who were free of ischemic heart disease and aged 20-93 years were followed for a mean of 22 years casts doubt on this association <ref>Christofferson et al. Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort studyBMJ 2011; 343:d5497</ref>. The mulivariate adjusted risk (hazard/odds ratios adjusted for confounders including [[cholesterol]] and [[triglyceride]] concentrations) indicated that arcus senilins was not an independent risk factor for [[atherosclerotic heart disease]]. | |||
==Refrences== | ==Refrences== | ||
Revision as of 14:28, 16 September 2011
| Arcus senilis | ||
| ICD-10 | H18.4 | |
|---|---|---|
| ICD-9 | 371.41 | |
| OMIM | 107800 | |
| DiseasesDB | 17120 | |
| MeSH | C11.204.299.070 | |
|
WikiDoc Resources for Arcus senilis |
|
Articles |
|---|
|
Most recent articles on Arcus senilis Most cited articles on Arcus senilis |
|
Media |
|
Powerpoint slides on Arcus senilis |
|
Evidence Based Medicine |
|
Clinical Trials |
|
Ongoing Trials on Arcus senilis at Clinical Trials.gov Trial results on Arcus senilis Clinical Trials on Arcus senilis at Google
|
|
Guidelines / Policies / Govt |
|
US National Guidelines Clearinghouse on Arcus senilis NICE Guidance on Arcus senilis
|
|
Books |
|
News |
|
Commentary |
|
Definitions |
|
Patient Resources / Community |
|
Patient resources on Arcus senilis Discussion groups on Arcus senilis Patient Handouts on Arcus senilis Directions to Hospitals Treating Arcus senilis Risk calculators and risk factors for Arcus senilis
|
|
Healthcare Provider Resources |
|
Causes & Risk Factors for Arcus senilis |
|
Continuing Medical Education (CME) |
|
International |
|
|
|
Business |
|
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Keywords and Synonyms: arcus corneae, arcus cornealis, Arcus senilis corneae, arcus adiposus, arcus. juvenilis (when it occurs in younger individuals), arcus lipoides corneae
Overview
Arcus senilis is a white or gray opaque ring in the corneal margin peripheral (corneal) opacity, present at birth, or appearing later in life, and becoming quite frequent in those over 50; it results from cholesterol deposits in or hyalinosis of the corneal stroma and may be associated with ocular defects or with familial hyperlipidemia.
Pathophysiology
It can be a sign of disturbance in lipid metabolism, an indicator of conditions such as hypercholesterolemia, hyperlipoproteinemia or hyperlipidemia.
Natural History, Complications, Prognosis
Association with Atherosclerosis
In the past, arcus has been said to be associated with atherosclerosis. However, a prospective population based cohort study (The Copenhagen City Heart Study), in which a total of 12,745 participants who were free of ischemic heart disease and aged 20-93 years were followed for a mean of 22 years casts doubt on this association [1]. The mulivariate adjusted risk (hazard/odds ratios adjusted for confounders including cholesterol and triglyceride concentrations) indicated that arcus senilins was not an independent risk factor for atherosclerotic heart disease.
Refrences
- ↑ Christofferson et al. Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort studyBMJ 2011; 343:d5497