Acute bronchitis laboratory tests

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

In addition to imaging modalities, laboratory tests may be conducted to diagnose acute bronchitis. Common laboratory tests include sputum sampling and blood testing. Findings generally indicate inflammation and the presence of pathogenic microorganisms.

Laboratory Tests

• A sputum sample showing neutrophil granulocytes (inflammatory white blood cells) and culture showing that has pathogenic microorganisms such as Streptococcus spp.
• A blood test would indicate inflammation (as indicated by a raised white blood cell count and elevated C-reactive protein).
• Neutrophils infiltrate the lung tissue, aided by damage to the airways caused by irritation.
• Damage caused by irritation of the airways leads to inflammation and leads to neutrophils being present
• Mucosal hypersecretion is promoted by a substance released by neutrophils
• Further obstruction to the airways is caused by more goblet cells in the small airways. This is typical of chronic bronchitis
• Although infection is not the reason or cause of chronic bronchitis it is seen to aid in sustaining the bronchitis.

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