Interstitial lung disease: Difference between revisions
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MeshID = D017563 | | MeshID = D017563 | | ||
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'''For the WikiPatient page for this topic, click [[Interstitial lung disease (patient information)|here]]''' | '''For the WikiPatient page for this topic, click [[Interstitial lung disease (patient information)|here]]''' | ||
{{CMG}} | {{CMG}} | ||
==Overview== | ==Overview== | ||
'''Interstitial lung disease (ILD)''', also known as '''diffuse parenchymal lung disease (DPLD)''', refers to a group of [[lung]] diseases (including '''idiopathic pulmonary fibrosis'''), affecting the [[Pulmonary alveolus|alveolar]] [[epithelium]], pulmonary [[capillary]] [[endothelium]], [[basement membrane]], perivascular and perilymphatic tissues. The term ILD is used to distinguish these diseases from obstructive airways diseases. Most types of ILD involve [[fibrosis]], but this is not essential; indeed fibrosis is often a later feature. Hence the term '''''pulmonary fibrosis''''' has fallen out of favor. | '''Interstitial lung disease (ILD)''', also known as '''diffuse parenchymal lung disease (DPLD)''', refers to a group of [[lung]] diseases (including '''idiopathic pulmonary fibrosis'''), affecting the [[Pulmonary alveolus|alveolar]] [[epithelium]], pulmonary [[capillary]] [[endothelium]], [[basement membrane]], perivascular and perilymphatic tissues. The term ILD is used to distinguish these diseases from obstructive airways diseases. Most types of ILD involve [[fibrosis]], but this is not essential; indeed fibrosis is often a later feature. Hence the term '''''pulmonary fibrosis''''' has fallen out of favor. | ||
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#* Lymphangitic [[carcinoma]]tosis | #* Lymphangitic [[carcinoma]]tosis | ||
== | ==Diagnosis== | ||
[[Image:PCP CAP CXR.JPG|left|thumb|Patients with [[Pneumocystis pneumonia (PCP)|pneumocystis pneumonia]] can present with interstitial lung disease, as seen in the reticular markings on this AP [[chest x-ray]]]] | [[Image:PCP CAP CXR.JPG|left|thumb|Patients with [[Pneumocystis pneumonia (PCP)|pneumocystis pneumonia]] can present with interstitial lung disease, as seen in the reticular markings on this AP [[chest x-ray]]]] | ||
Investigation is tailored towards the symptoms and signs. Most patients have blood testing, chest [[x-ray]], pulmonary function testing, and high resolution [[computerized tomography|CT]] thorax. | Investigation is tailored towards the symptoms and signs. Most patients have blood testing, chest [[x-ray]], pulmonary function testing, and high resolution [[computerized tomography|CT]] thorax. | ||
== Treatment == | ==Treatment== | ||
ILD is not a single disease, but encompasses many different pathological processes. Hence treatment is different for each disease. | ILD is not a single disease, but encompasses many different pathological processes. Hence treatment is different for each disease. | ||
Revision as of 20:27, 26 September 2011
Template:DiseaseDisorder infobox
For the WikiPatient page for this topic, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Interstitial lung disease (ILD), also known as diffuse parenchymal lung disease (DPLD), refers to a group of lung diseases (including idiopathic pulmonary fibrosis), affecting the alveolar epithelium, pulmonary capillary endothelium, basement membrane, perivascular and perilymphatic tissues. The term ILD is used to distinguish these diseases from obstructive airways diseases. Most types of ILD involve fibrosis, but this is not essential; indeed fibrosis is often a later feature. Hence the term pulmonary fibrosis has fallen out of favor.
Causes
ILD may be classified according to the cause: -
- Inhaled substances
- Inorganic
- Organic
- Drug induced
- Connective tissue disease
- Infection
- Atypical pneumonia
- Pneumocystis pneumonia (PCP)
- Tuberculosis
- Idiopathic
- Malignancy
- Lymphangitic carcinomatosis
Diagnosis
Investigation is tailored towards the symptoms and signs. Most patients have blood testing, chest x-ray, pulmonary function testing, and high resolution CT thorax.
Treatment
ILD is not a single disease, but encompasses many different pathological processes. Hence treatment is different for each disease.
If a specific occupational exposure cause is found, the person should avoid that environment. If a drug cause is suspected, that drug should be discontinued.
Many idiopathic and connective tissue-based causes of ILD are treated with prednisolone. Some patients respond to immunosuppressant treatment. Patients with hypoxemia may be given supplemental oxygen.
Template:Respiratory pathology Template:SIB
de:Interstitielle Lungenerkrankung fi:Keuhkoparenkyymisairaudet