Alagille syndrome natural history: Difference between revisions
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{{Alagille syndrome}} | |||
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==Overview== | |||
The prognosis for Alagille syndrome patients varies largely on choice of treatment. | |||
==Prognosis== | |||
Mortality is approximately 10%, with vascular accidents, cardiac disease, and liver disease accounting for most of the deaths. Vascular anomalies account for 34% of the mortality in this population <ref name="pmid14993126">{{cite journal| author=Kamath BM, Spinner NB, Emerick KM, Chudley AE, Booth C, Piccoli DA et al.| title=Vascular anomalies in Alagille syndrome: a significant cause of morbidity and mortality. | journal=Circulation | year= 2004 | volume= 109 |issue= 11 | pages= 1354-8 | pmid=14993126 | doi=10.1161/01.CIR.0000121361.01862.A4 | pmc= |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14993126 }} </ref>. | Mortality is approximately 10%, with vascular accidents, cardiac disease, and liver disease accounting for most of the deaths. Vascular anomalies account for 34% of the mortality in this population <ref name="pmid14993126">{{cite journal| author=Kamath BM, Spinner NB, Emerick KM, Chudley AE, Booth C, Piccoli DA et al.| title=Vascular anomalies in Alagille syndrome: a significant cause of morbidity and mortality. | journal=Circulation | year= 2004 | volume= 109 |issue= 11 | pages= 1354-8 | pmid=14993126 | doi=10.1161/01.CIR.0000121361.01862.A4 | pmc= |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14993126 }} </ref>. | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Pediatrics]] | |||
[[Category:Gastroenterology]] | |||
[[Category:Genetic disorders]] | |||
[[Category:Rare diseases]] | |||
[[Category:Hepatology]] | |||
[[Category:Mature chapter]] | |||
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{{WS}} | |||
Revision as of 17:29, 23 September 2011
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Alagille syndrome Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Alagille syndrome natural history On the Web |
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American Roentgen Ray Society Images of Alagille syndrome natural history |
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Risk calculators and risk factors for Alagille syndrome natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The prognosis for Alagille syndrome patients varies largely on choice of treatment.
Prognosis
Mortality is approximately 10%, with vascular accidents, cardiac disease, and liver disease accounting for most of the deaths. Vascular anomalies account for 34% of the mortality in this population [1].
References
- ↑ Kamath BM, Spinner NB, Emerick KM, Chudley AE, Booth C, Piccoli DA; et al. (2004). "Vascular anomalies in Alagille syndrome: a significant cause of morbidity and mortality". Circulation. 109 (11): 1354–8. doi:10.1161/01.CIR.0000121361.01862.A4. PMID 14993126.