Alteplase pharmacokinetics and molecular data: Difference between revisions

Latest revision as of 22:27, 21 July 2014

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-{{CMG}}
+#REDIRECT [[Alteplase#Pharmacology]]
-==Pharmacokinetics==
-===Absorption===
-C max is 3 to 4 mg/L.
-===Distribution===
-Vd is 2.8 to 4.6 L and doubles at steady state.
-===Elimination===
-Initial t ½ is less than 5 min. Plasma Cl is 380 to 570 mL/min; total body Cl is 34.3 to 38.4 L/h. More than 80% is cleared from plasma within 10 min.
-{{FDA}}
-[[Category:Drugs]]