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{{drugbox |
{{drugbox |
| IUPAC_name = (5''S'',8''S'')-5-{[(1''S'')-1-ethoxycarbonyl-3-phenyl-propyl]<br>amino}-6-oxo-1,7-diazabicyclo[5.4.0]undecane-8-<br>carboxylic acid
| IUPAC_name = (5''S'',8''S'')-5-{[(1''S'')-1-ethoxycarbonyl-3-phenyl-propyl]<br>amino}-6-oxo-1,7-diazabicyclo[5.4.0]undecane-8-<br>carboxylic acid
| image = Cilazapril.svg
| image = Cilazapril.PNG
| CAS_number = 92077-78-6
| CAS_number = 92077-78-6
| ATC_prefix = C09
| ATC_prefix = C09
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| routes_of_administration =  
| routes_of_administration =  
}}
}}
'''Cilazapril''' is a [[pyridazine]] [[ACE inhibitor]].


{{ACE inhibitors}}
{{CMG}} {{SS}}
{{drug-stub}}
 
'''Cilazapril''' is an [[angiotensin-converting enzyme]] inhibitor ([[ACE inhibitor]]) used for the treatment of [[hypertension]] and [[congestive heart failure]].<ref>{{cite pmid|1712267}}</ref><ref>{{cite book|title=Austria-Codex|editor=Jasek, W|publisher=Österreichischer Apothekerverlag|location=Vienna|year=2007|edition=2007/2008|isbn=978-3-85200-181-4|language=German}}</ref> It is branded as '''Inhibace''' in Canada and other countries, '''Vascace''' and '''Dynorm''' in a number of European countries, among many other names. None of these are available in the [[United States]] as of May 2010.<ref>Drugs.com: [http://www.drugs.com/international/cilazapril.html Cilazapril]</ref>
 
Of the eight possible [[stereoisomers]], only the all-''S'' form is medically viable.{{citation needed|date=February 2012}}
 
{{Reflist|2}}
 
[[Category:ACE inhibitors]]
[[Category:ACE inhibitors]]
[[Category:Cardiovascular Drugs]][[Category:Drugs]]


[[hr:Cilazapril]]
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Revision as of 19:27, 23 July 2014

Cilazapril
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC22H33N3O6
Molar mass435.514 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Sheng Shi, M.D. [2]

Cilazapril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure.[1][2] It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries, among many other names. None of these are available in the United States as of May 2010.[3]

Of the eight possible stereoisomers, only the all-S form is medically viable.[citation needed]

  1. ↑ PMID 1712267 (PMID 1712267)
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  2. ↑ Jasek, W, ed. (2007). Austria-Codex (in German) (2007/2008 ed.). Vienna: Österreichischer Apothekerverlag. ISBN 978-3-85200-181-4.
  3. ↑ Drugs.com: Cilazapril


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