Paromomycin sulfate: Difference between revisions
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'''Paromomycin sulfate''' (brand name '''Humatin''') is a drug that fights intestinal infections such as [[cryptosporidiosis]] and amoeba infection, or [[amoebiasis]] and was developed as a therapeutic against [[visceral leishmaniasis]] by the [[Institute for OneWorld Health]]. Paromomycin was granted [[orphan drug]] status in 2005<ref>{{cite press release | '''Paromomycin sulfate''' (brand name '''Humatin''') is a drug that fights intestinal infections such as [[cryptosporidiosis]] and amoeba infection, or [[amoebiasis]] and was developed as a therapeutic against [[visceral leishmaniasis]] by the [[Institute for OneWorld Health]]. Paromomycin was granted [[orphan drug]] status in 2005<ref>{{cite press release | ||
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Revision as of 14:47, 20 August 2012
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Clinical data | |
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Pregnancy category |
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Routes of administration | Oral, intramuscular |
ATC code | |
Legal status | |
Legal status |
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Pharmacokinetic data | |
Bioavailability | None |
Metabolism | None |
Elimination half-life | ? |
Excretion | Fecal |
Identifiers | |
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CAS Number | |
PubChem CID | |
DrugBank | |
E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C23H47N5O18S |
Molar mass | 615.629 g/mol |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Paromomycin sulfate (brand name Humatin) is a drug that fights intestinal infections such as cryptosporidiosis and amoeba infection, or amoebiasis and was developed as a therapeutic against visceral leishmaniasis by the Institute for OneWorld Health. Paromomycin was granted orphan drug status in 2005[1] and was approved by the Drug Controller General of India in September 2006 for treatment of visceral leishmaniasis.[2]
Paromomycin inhibits protein synthesis by binding to 16S ribosomal RNA.[3]
References
- ↑ "Institute for OneWorld Health Drug Receives "Orphan" Designation From U.S. and European Regulatory Agencies" (Press release). Institute for OneWorld Health. 23 May 2005. Retrieved 2007-02-10.
- ↑ "New cure for deadly visceral leishmaniasis (kala-azar) approved by government of India" (Press release). Institute for OneWorld Health. 8 September 2006. Retrieved 2007-02-10.
- ↑ Vicens, Quentin (2001). "Crystal Structure of Paromomycin Docked into the Eubacterial Ribosomal Decoding A Site". Structure. 9 (8): 647&ndash, 658. doi:10.1016/S0969-2126(01)00629-3. PMID 11587639. Retrieved 2007-02-10. Unknown parameter
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Template:Antidiarrheals, intestinal anti-inflammatory/anti-infective agents
de:Paromomycin Template:Jb1 Template:WH Template:WikiDoc Sources
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