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'''Cefazolin''' ([[International Nonproprietary Name|INN]]), also known as '''cefazoline''' or '''cephazolin''', is a first generation [[cephalosporin]] [[antibiotic]].
'''Cefazolin''' ([[International Nonproprietary Name|INN]]), also known as '''cefazoline''' or '''cephazolin''', is a first generation [[cephalosporin]] [[antibiotic]].
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[[Category:Cephalosporin antibiotics]]
[[Category:Cephalosporin antibiotics]]
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[[fr:Céfazoline]]
[[fr:Céfazoline]]

Revision as of 23:35, 8 August 2012

Cefazolin
File:Cefazolin.png
Clinical data
Pregnancy
category
  • AU: B1
  • US: B (No risk in non-human studies)
Routes of
administration
Intravenous, intramuscular
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityNA
Metabolism?
Elimination half-life1.8 hours (given IV)
2 hours (given IM)
ExcretionRenal, unchanged
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC14H13N8O4S3
Molar mass454.51 g/mol

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Cefazolin (INN), also known as cefazoline or cephazolin, is a first generation cephalosporin antibiotic.

The drug is usually administrated either by intramuscular injection (injection into a large muscle) or intravenous infusion (intravenous fluid into a vein).

Indications

Cefazolin is mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. These organisms are common on normal human skin. Resistance to cefazolin is seen in several species of bacteria.

Side effects

Side effects from cefazolin are not common. Possible side effects include:

  • diarrhea
  • stomach pain
  • upset stomach
  • vomiting

Cefazolin is marketed under the following brand names: Ancef®, Cefacidal®, Cefamezin®, Cefrina®, Elzogram®, Faxilen®, Gramaxin®, Kefazol®, Kefol®, Kefzol®, Kefzolan®, Kezolin®, Novaporin®, and Zolicef®

External links

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