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'''Cefixime''' is an oral third generation [[cephalosporin]] [[antibiotic]].  It was sold under the trade name '''Suprax''' in the USA, until 2003 when it was taken off the market by drug manufacturer [[Wyeth]] after its [[patent]] expired. the oral suspension form of "Suprax" was re-launched by Lupin in the USA.  Cefixime is still available in [[Canada]].  It is used to treat [[gonorrhea]]<ref name="McMillan-2007">{{cite journal | author=McMillan A, Young H. | title=The treatment of pharyngeal gonorrhoea with a single oral dose of cefixime. | journal=Int J STD AIDS | year=2007 | volume=18 | issue=4 | pages=253-4 | id=PMID 17509176}}</ref>, [[tonsilitis]]<ref name="Adam-1995">{{cite journal | author=Adam D, Hostalek U, Tröster K. | title=5-day cefixime therapy for bacterial pharyngitis and/or tonsillitis: comparison with 10-day penicillin V therapy. | journal=Infection | year=1995 | volume=23 | issue=Suppl 2 | pages=S83-6 | id=PMID 8537138}}</ref>, and [[pharyngitis]]<ref name="Adam-1995" />.
'''Cefixime''' is an oral third generation [[cephalosporin]] [[antibiotic]].  It was sold under the trade name '''Suprax''' in the USA, until 2003 when it was taken off the market by drug manufacturer [[Wyeth]] after its [[patent]] expired. the oral suspension form of "Suprax" was re-launched by Lupin in the USA.  Cefixime is still available in [[Canada]].  It is used to treat [[gonorrhea]]<ref name="McMillan-2007">{{cite journal | author=McMillan A, Young H. | title=The treatment of pharyngeal gonorrhoea with a single oral dose of cefixime. | journal=Int J STD AIDS | year=2007 | volume=18 | issue=4 | pages=253-4 | id=PMID 17509176}}</ref>, [[tonsilitis]]<ref name="Adam-1995">{{cite journal | author=Adam D, Hostalek U, Tröster K. | title=5-day cefixime therapy for bacterial pharyngitis and/or tonsillitis: comparison with 10-day penicillin V therapy. | journal=Infection | year=1995 | volume=23 | issue=Suppl 2 | pages=S83-6 | id=PMID 8537138}}</ref>, and [[pharyngitis]]<ref name="Adam-1995" />.
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Revision as of 23:36, 8 August 2012

Cefixime
File:Cefixime.png
Clinical data
Pregnancy
category
  • B
Routes of
administration
Oral
ATC code
Pharmacokinetic data
Bioavailability40% to 50%
Protein bindingApproximately 60%
Elimination half-lifeVariable
Average 3 to 4 hours
ExcretionRenal and biliary
Identifiers
CAS Number
PubChem CID
DrugBank
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC16H15N5O7S2
Molar mass453.452 g/mol

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Cefixime is an oral third generation cephalosporin antibiotic. It was sold under the trade name Suprax in the USA, until 2003 when it was taken off the market by drug manufacturer Wyeth after its patent expired. the oral suspension form of "Suprax" was re-launched by Lupin in the USA. Cefixime is still available in Canada. It is used to treat gonorrhea[1], tonsilitis[2], and pharyngitis[2].

References

  1. McMillan A, Young H. (2007). "The treatment of pharyngeal gonorrhoea with a single oral dose of cefixime". Int J STD AIDS. 18 (4): 253–4. PMID 17509176.
  2. 2.0 2.1 Adam D, Hostalek U, Tröster K. (1995). "5-day cefixime therapy for bacterial pharyngitis and/or tonsillitis: comparison with 10-day penicillin V therapy". Infection. 23 (Suppl 2): S83–6. PMID 8537138.

External links

th:เซฟิกซิม

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