Cefotiam: Difference between revisions

	WikiDoc Resources for Cefotiam
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Cefotiam
	File:Cefotiam.svg
Clinical data
Routes of; administration	Intravenous, intramuscular
ATC code	J01DC07 (WHO) ;
Pharmacokinetic data
Bioavailability	60% (intramuscular)
Protein binding	40%
Metabolism	Nil
Elimination half-life	Approximately 1 hour
Excretion	Renal
Identifiers
	IUPAC name (6R,7R)-7-{[2-(2-amino-1,3-thiazol-4-yl)acetyl]; amino}-3-{[1-(2-dimethylaminoethyl)tetrazol-5-yl]; sulfanylmethyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]; oct-2-ene-2-carboxylic acid;
CAS Number	61622-34-2;
PubChem CID	43708;
DrugBank	APRD00855;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C18H23N9O4S3
Molar mass	525.631 g/mol

Revision as of 23:36, 8 August 2012

Cefotiam is a second-generation cephalosporin antibiotic.

Müller R, Böttger C, Wichmann G (2003). "Suitability of cefotiam and cefuroxime axetil for the perioperative short-term prophylaxis in tonsillectomy patients". Arzneimittelforschung. 53 (2): 126–32. PMID 12642969.
Kolben M, Mandoki E, Ulm K, Freitag K (2001). "Randomized trial of cefotiam prophylaxis in the prevention of postoperative infectious morbidity after elective cesarean section". Eur J Clin Microbiol Infect Dis. 20 (1): 40–2. PMID 11245321.
Shimizu S, Chen K, Miyakawa S (1996). "Cefotiam-induced contact urticaria syndrome: an occupational condition in Japanese nurses". Dermatology. 192 (2): 174–6. PMID 8829507.

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 '''Cefotiam''' is a second-generation [[cephalosporin]] [[antibiotic]].
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 [[Category:Tetrazoles]]
 [[Category:Cephalosporin antibiotics]]
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 [[th:เซโฟเตียม]]
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v t e Antibacterials: cell wall disruption (J01C-J01D)
Internal to membrane/ (inhibit peptidoglycan subunit synthesis and transport)	Template:Navbox subgroup
Glycopeptide/ (inhibit PG chain elongation)	Vancomycin # (Oritavancin, Telavancin) · Teicoplanin (Dalbavancin) · Ramoplanin
Beta-lactams/ (inhibit cross-links with PBP)	Template:Navbox subgroup
Other	Template:Navbox subgroup
# = WHO-EM

Clinical data
File:Cefotiam.svg
Routes of administration	Intravenous, intramuscular
ATC code	J01DC07 (WHO)
Pharmacokinetic data
Bioavailability	60% (intramuscular)
Protein binding	40%
Metabolism	Nil
Elimination half-life	Approximately 1 hour
Excretion	Renal
Identifiers
IUPAC name (6R,7R)-7-{[2-(2-amino-1,3-thiazol-4-yl)acetyl] amino}-3-{[1-(2-dimethylaminoethyl)tetrazol-5-yl] sulfanylmethyl}-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylic acid
CAS Number	61622-34-2
PubChem CID	43708
DrugBank	APRD00855
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₈H₂₃N₉O₄S₃
Molar mass	525.631 g/mol