Propamidine: Difference between revisions

Propamidine
	Ball-and-stick model
Names
	IUPAC name 4,4'-[propane-1,3-diylbis(oxy)]dibenzenecarboximidamide
Identifiers
CAS Number	104-32-5 ; 140-63-6 (isethionate) ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL23013 ;
ChemSpider	58475 ;
ECHA InfoCard	Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
PubChem CID	64949;
	InChI InChI=1S/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21) Key: WTFXJFJYEJZMFO-UHFFFAOYSA-N ; InChI=1/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21) Key: WTFXJFJYEJZMFO-UHFFFAOYAO;
	SMILES O(c1ccc(cc1)C(=[N@H])N)CCCOc2ccc(C(=[N@H])N)cc2;
Properties
Chemical formula	C17H20N4O2
Molar mass	312.37 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	verify (what is ?)
	Infobox references

VisualWikitext

Revision as of 13:30, 13 April 2015

Template:Chembox E number

Propamidine is an antiseptic and disinfectant.

Propamidine isethionate, the salt of propamidine with isethionic acid, is used in the treatment of Acanthamoeba infection.^[1]

References

↑ Perrine D, Chenu JP, Georges P, Lancelot JC, Saturnino C, Robba M (February 1995). "Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga". Antimicrob. Agents Chemother. 39 (2): 339–42. doi:10.1128/aac.39.2.339. PMC 162538. PMID 7726493.

Template:Antiseptics and disinfectants Template:Agents against amoebozoa

Template:Natural-phenol-stub Template:Antiinfective-drug-stub Template:Dermatologic-drug-stub

[pmid7726493-1] Perrine D, Chenu JP, Georges P, Lancelot JC, Saturnino C, Robba M (February 1995). "Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga". Antimicrob. Agents Chemother. 39 (2): 339–42. doi:10.1128/aac.39.2.339. PMC 162538. PMID 7726493.

[1]

@@ Line 1: / Line 1: @@
-{{Chembox new
+{{chembox
-|ImageFile=propamidine.png
+| Verifiedfields = changed
-|ImageSize=
+| UNII_Ref = {{fdacite|correct|FDA}}
-|IUPACName=4-[3-(4-carbamimidoylphenoxy)propoxy]benzamidine
+| UNII = G20G12V769
-|OtherNames=
+| verifiedrevid = 464216026
+| ImageFile = propamidine.png
+| ImageSize = 240px
+| ImageName = Skeletal formula
+| ImageFile1 = Propamidine-3D-balls.png
+| ImageSize1 = 240px
+| ImageName1 = Ball-and-stick model
+| IUPACName = 4,4'-[propane-1,3-diylbis(oxy)]dibenzenecarboximidamide
+| OtherNames =
 |Section1= {{Chembox Identifiers
-|  CASNo=104-32-5
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
-|  PubChem=64949
+| ChemSpiderID = 58475
-|  SMILES=C1=CC(=CC=C1C(=N)N)OCCCOC2=CC=C(C=C2)C(=N)N
+| InChI = 1/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21)
-  }}
+| InChIKey = WTFXJFJYEJZMFO-UHFFFAOYAO
+| ChEMBL_Ref = {{ebicite|correct|EBI}}
+| ChEMBL = 23013
+| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChI = 1S/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21)
+| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChIKey = WTFXJFJYEJZMFO-UHFFFAOYSA-N
+| CASNo_Ref = {{cascite|changed|??}}
+| CASNo=104-32-5
+| CASNo2_Ref = {{cascite|changed|??}}
+| CASNo2 = 140-63-6
+| CASNo2_Comment = (isethionate)
+| PubChem=64949
+| ATCCode_prefix = D08
+| ATCCode_suffix = AC03
+| ATC_Supplemental = {{ATC|S01|AX15}}
+| SMILES = O(c1ccc(cc1)C(=[N@H])N)CCCOc2ccc(C(=[N@H])N)cc2
+}}
 |Section2= {{Chembox Properties
-|  Formula=C<sub>17</sub>H<sub>20</sub>N<sub>4</sub>O<sub>2</sub>
+| Formula=C<sub>17</sub>H<sub>20</sub>N<sub>4</sub>O<sub>2</sub>
-|  MolarMass=312.366
+| MolarMass=312.37 g/mol
-|  Appearance=
+| Appearance=
-|  Density=
+| Density=
-|  MeltingPt=
+| MeltingPt=
-|  BoilingPt=
+| BoilingPt=
-|  Solubility=
+| Solubility=
    }}
 |Section3= {{Chembox Hazards
-|  MainHazards=
+| MainHazards=
-|  FlashPt=
+| FlashPt=
-|  Autoignition=
+| AutoignitionPt=
    }}
 }}
 '''Propamidine''' is an [[antiseptic]] and [[disinfectant]].
+Propamidine isethionate, the [[salt (chemistry)|salt]] of propamidine with [[isethionic acid]], is used in the treatment of ''[[Acanthamoeba]]'' infection.<ref name="pmid7726493">{{cite journal |author=Perrine D, Chenu JP, Georges P, Lancelot JC, Saturnino C, Robba M |title=Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga |journal=Antimicrob. Agents Chemother. |volume=39 |issue=2 |pages=339–42 |date=February 1995 |pmid=7726493 |pmc=162538 |doi= 10.1128/aac.39.2.339|url=http://aac.asm.org/cgi/pmidlookup?view=long&pmid=7726493}}</ref>
-{{pharmacology-stub}}
+==References==
+{{reflist}}
 {{Antiseptics and disinfectants}}
+{{Agents against amoebozoa}}
 [[Category:Amidines]]
 [[Category:Antiseptics]]
+[[Category:Antiparasitic agents]]
+[[Category:Phenol ethers]]
+{{Natural-phenol-stub}}
+{{antiinfective-drug-stub}}
+{{dermatologic-drug-stub}}

Propamidine: Difference between revisions

Revision as of 13:30, 13 April 2015

References

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