Cardiology overview pharmacology: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
Line 8: | Line 8: | ||
==Drug Food Interactions== | ==Drug Food Interactions== | ||
===Grapefruit=== | ===Grapefruit=== | ||
* Grapefruit juice inhibits the Cyp 3A4 enzyme which reduces the breakdown of drugs. Grapefruit juice also increases the p- glycoprotein in the intestines which increases drug absorption. | |||
* [[Amiodarone]] | * [[Amiodarone]] | ||
* [[Nifedipine]] | * [[Nifedipine]] |
Revision as of 17:23, 31 October 2011
Cardiology Overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Drug Drug Interactions
- Cyclosporin co-administration is associated with a higher rate of myositis among statin users as a result of inhibition of CYP3A4. The exception is pravastatin in which this is not a problem.
Drug Food Interactions
Grapefruit
- Grapefruit juice inhibits the Cyp 3A4 enzyme which reduces the breakdown of drugs. Grapefruit juice also increases the p- glycoprotein in the intestines which increases drug absorption.
- Amiodarone
- Nifedipine
- Simvastatin