Pulmonary hypertension right heart catheterization: Difference between revisions
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{{Pulmonary hypertension}} | {{Pulmonary hypertension}} | ||
{{CMG}}; '''Assistant Editor(s)-in-Chief:''' [[User:Ralph Matar|Ralph Matar]] | {{CMG}}; '''Assistant Editor(s)-in-Chief:''' [[User:Ralph Matar|Ralph Matar]] | ||
==Overview== | |||
In primary pulmonary hypertension the [[pulmonary artery]] diastolic pressure is much higher than the [[pulmonary capillary wedge pressure]]. If the pulmonary hypertension is due to left-sided heart failure, and the pulmonary artery diastolic pressure in the pulmonary capillary wedge pressure will be similar. In the cardiac catheterization laboratory, inhaled nitric oxide is administered to determine if the pulmonary vasculature is still reactive or if the obstructionist fixed. It is dangerous to give nifedipine IV as a test. This could lead to a dangerous episode of [[hypotension]]. | In primary pulmonary hypertension the [[pulmonary artery]] diastolic pressure is much higher than the [[pulmonary capillary wedge pressure]]. If the pulmonary hypertension is due to left-sided heart failure, and the pulmonary artery diastolic pressure in the pulmonary capillary wedge pressure will be similar. In the cardiac catheterization laboratory, inhaled nitric oxide is administered to determine if the pulmonary vasculature is still reactive or if the obstructionist fixed. It is dangerous to give nifedipine IV as a test. This could lead to a dangerous episode of [[hypotension]]. | ||
==Right heart Catheterization | ==Right heart Catheterization == | ||
Cardiac catheterization is still the gold standard for diagnosing, assesing severity, and determining prognosis and response to therapy in pulmonary hypertension. | Cardiac catheterization is still the '''gold standard''' for diagnosing, assesing severity, and determining prognosis and response to therapy in pulmonary hypertension. | ||
Right heart catheterization allows for determination of: | Right heart catheterization allows for determination of: | ||
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*Fick’s method is reliable in patients with PAH for the measurement of cardiac output: | *Fick’s method is reliable in patients with PAH for the measurement of cardiac output: | ||
[[Image:Fick's principal for calculating cardiac output.png|600px]] | [[Image:Fick's principal for calculating cardiac output.png|600px]] | ||
*Since end-expiratory intrathoracic pressure most closely correlates with atmospheric pressure, it is important that all right ventricular, pulmonary artery, pulmonary wedge, and left ventricular pressures be measured at end-expiration | *Since end-expiratory intrathoracic pressure most closely correlates with atmospheric pressure, it is important that all right ventricular, pulmonary artery, pulmonary wedge, and left ventricular pressures be measured at end-expiration | ||
*This procedure has been shown to be safe, with no deaths reported in the NIH registry study. In addition, a recent study reported a procedure-related mortality of 0.055%. | *This procedure has been shown to be safe, with no deaths reported in the NIH registry study. In addition, a recent study reported a procedure-related mortality of 0.055%. | ||
==References== | ==References== | ||
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{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Revision as of 18:48, 27 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor(s)-in-Chief: Ralph Matar
Overview
In primary pulmonary hypertension the pulmonary artery diastolic pressure is much higher than the pulmonary capillary wedge pressure. If the pulmonary hypertension is due to left-sided heart failure, and the pulmonary artery diastolic pressure in the pulmonary capillary wedge pressure will be similar. In the cardiac catheterization laboratory, inhaled nitric oxide is administered to determine if the pulmonary vasculature is still reactive or if the obstructionist fixed. It is dangerous to give nifedipine IV as a test. This could lead to a dangerous episode of hypotension.
Right heart Catheterization
Cardiac catheterization is still the gold standard for diagnosing, assesing severity, and determining prognosis and response to therapy in pulmonary hypertension.
Right heart catheterization allows for determination of:
1-Presence or absence of pulmonary hypertension, define the underlying etiology, and determine the prognosis.
2- Prognostic markers such as right atrial pressure, cardiac output, and mean pulmonary artery pressure.
3- Pulmonary venous pressures by measuring pulmonary capillary wedge pressure (PCWP). Pulmonary arterial hypertension (PAH) is defined by a PCWP of 15 mmHg or less knowing that the normal PCWP or left ventricular end diastolic pressure (LVEDP) is less than 8 mmHg.
- Fick’s method is reliable in patients with PAH for the measurement of cardiac output:
- Since end-expiratory intrathoracic pressure most closely correlates with atmospheric pressure, it is important that all right ventricular, pulmonary artery, pulmonary wedge, and left ventricular pressures be measured at end-expiration
- This procedure has been shown to be safe, with no deaths reported in the NIH registry study. In addition, a recent study reported a procedure-related mortality of 0.055%.