Alprazolam contraindications: Difference between revisions
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== | ==List of contraindications== | ||
Alprazolam is contraindicated in patients with known sensitivity to this drug or other benzodiazepines. Alprazolam may be used in patients with open angle glaucoma who are receiving appropriate therapy, but is contraindicated in patients with acute narrow angle glaucoma. | <font size="4">[[Alprazolam contraindications#Benzodiazepine sensitivity|Benzodiazepine sensitivity]]</font> | ||
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Alprazolam is contraindicated with ketoconazole and itraconazole, since these medications significantly impair the oxidative metabolism mediated by cytochrome P450 3A (CYP3A). | <br> | ||
<font size="4">[[Alprazolam contraindications#Narrow angle glaucoma|Narrow angle glaucoma]]</font> | |||
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<font size="4">[[Alprazolam contraindications#Ketoconazole & itraconazole|Ketoconazole & itraconazole]]</font> | |||
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===Benzodiazepine sensitivity=== | |||
Alprazolam is contraindicated in patients with known sensitivity to this drug or other benzodiazepines. ''[[Alprazolam contraindications#List of contraindications|Return to top]]'' | |||
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===Narrow angle glaucoma=== | |||
Alprazolam may be used in patients with open angle glaucoma who are receiving appropriate therapy, but is contraindicated in patients with acute narrow angle glaucoma. ''[[Alprazolam contraindications#List of contraindications|Return to top]]'' | |||
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===Ketoconazole & itraconazole=== | |||
Alprazolam is contraindicated with ketoconazole and itraconazole, since these medications significantly impair the oxidative metabolism mediated by cytochrome P450 3A (CYP3A). ''[[Alprazolam contraindications#List of contraindications|Return to top]]'' | |||
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{{FDA}} | {{FDA}} |
Revision as of 20:39, 19 December 2011
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
List of contraindications
Benzodiazepine sensitivity
Narrow angle glaucoma
Ketoconazole & itraconazole
Benzodiazepine sensitivity
Alprazolam is contraindicated in patients with known sensitivity to this drug or other benzodiazepines. Return to top
Narrow angle glaucoma
Alprazolam may be used in patients with open angle glaucoma who are receiving appropriate therapy, but is contraindicated in patients with acute narrow angle glaucoma. Return to top
Ketoconazole & itraconazole
Alprazolam is contraindicated with ketoconazole and itraconazole, since these medications significantly impair the oxidative metabolism mediated by cytochrome P450 3A (CYP3A). Return to top
Adapted from the FDA Package Insert.