Kaposi's sarcoma pathophysiology: Difference between revisions
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Revision as of 19:06, 12 September 2012
Kaposi's sarcoma Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Kaposi's sarcoma pathophysiology On the Web |
American Roentgen Ray Society Images of Kaposi's sarcoma pathophysiology |
Risk calculators and risk factors for Kaposi's sarcoma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Despite its name, it is generally not considered a true sarcoma, which is a tumor arising from mesenchymal tissue. KS actually arises as a cancer of lymphatic endothelium and forms vascular channels that fill with blood cells, giving the tumor its characteristic bruise-like appearance.
KS lesions contain tumor cells with a characteristic abnormal elongated shape, called spindle cells. The tumor is highly vascular, containing abnormally dense and irregular blood vessels, which leak red blood cells into the surrounding tissue and give the tumor its dark color. Inflammation around the tumor may produce swelling and pain.