Osteosarcoma overview: Difference between revisions
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Created page with "{{CMG}} {{Osteosarcoma}} ==Overview== '''Osteosarcoma''' is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies. There is a prefere..." |
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==Overview== | ==Overview== | ||
'''Osteosarcoma''' is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies. There is a preference for the [[metaphysis|metaphyseal]] region of tubular long [[bone]]s. 50% of cases occur around the [[knee]]. It is a malignant connective (soft) tissue tumor whose neoplastic cells present [[osteoblast]]ic differentiation and form tumoral bone. | '''Osteosarcoma''' is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies. There is a preference for the [[metaphysis|metaphyseal]] region of tubular long [[bone]]s. 50% of cases occur around the [[knee]]. It is a malignant connective (soft) tissue tumor whose neoplastic cells present [[osteoblast]]ic differentiation and form tumoral bone. | ||
==Subtypes <small><ref>MD Murphey, MR Robbin, GA McRae, DJ Flemming, HT Temple, and MJ Kransdorf. [http://radiographics.rsnajnls.org/cgi/content/abstract/17/5/1205 The many faces of osteosarcoma.] RadioGraphics 1997 17: 1205-1231.</ref></small>== | |||
*Intramedullary | |||
**High-grade | |||
**Telangiectatic | |||
**Low-grade | |||
**Small cell | |||
**Osteosarcomatosis | |||
**Gnathic | |||
*Surface | |||
**Intracortical | |||
**Parosteal | |||
**Periosteal | |||
**High-grade | |||
*Extraskeletal | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Revision as of 14:43, 18 January 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Osteosarcoma is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies. There is a preference for the metaphyseal region of tubular long bones. 50% of cases occur around the knee. It is a malignant connective (soft) tissue tumor whose neoplastic cells present osteoblastic differentiation and form tumoral bone.
Subtypes [1]
- Intramedullary
- High-grade
- Telangiectatic
- Low-grade
- Small cell
- Osteosarcomatosis
- Gnathic
- Surface
- Intracortical
- Parosteal
- Periosteal
- High-grade
- Extraskeletal
References
- ↑ MD Murphey, MR Robbin, GA McRae, DJ Flemming, HT Temple, and MJ Kransdorf. The many faces of osteosarcoma. RadioGraphics 1997 17: 1205-1231.