Chronic myelogenous leukemia epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
==Epidemiology== | |||
CML occurs in all age groups, but most commonly in the middle-aged and elderly. Its annual [[incidence (epidemiology)|incidence]] is 1–2 per 100,000 people, and slightly more men than women are affected. CML represents about 15–20% of all cases of adult leukemia in Western populations.<ref name="Faderl1990">{{cite journal|title=Chronic myelogenous leukemia: biology and therapy.|author=Faderl S, Talpaz M, Estrov Z, Kantarjian HM|journal=Annals of Internal Medicine|date=1999|volume=131|issue=3|pages=207-219|pmid=10428738}}</ref> The only well-described risk factor for CML is exposure to [[ionizing radiation]]; for example, increased rates of CML were seen in people exposed to the atomic bombings of Hiroshima and Nagasaki.<ref>{{cite journal|title=Radiogenic leukemia revisited|author=Moloney WC|date=1987|journal=Blood|volume=70|issue=4|pages=905-908|pmid=3477299}}</ref> | |||
==References== | ==References== | ||
Revision as of 15:55, 20 January 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Epidemiology
CML occurs in all age groups, but most commonly in the middle-aged and elderly. Its annual incidence is 1–2 per 100,000 people, and slightly more men than women are affected. CML represents about 15–20% of all cases of adult leukemia in Western populations.[1] The only well-described risk factor for CML is exposure to ionizing radiation; for example, increased rates of CML were seen in people exposed to the atomic bombings of Hiroshima and Nagasaki.[2]