Vulvar cancer: Difference between revisions

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==Treatment==
==Treatment==
[[Vulvar cancer medical therapy|Medical therapy]] | [[Vulvar cancer surgery|Surgical options]] | [[Vulvar cancer primary prevention|Primary prevention]]  | [[Vulvar cancer secondary prevention|Secondary prevention]] | [[Vulvar cancer cost-effectiveness of therapy|Financial costs]] | [[Vulvar cancer future or investigational therapies|Future therapies]]
[[Vulvar cancer medical therapy|Medical therapy]] | [[Vulvar cancer surgery|Surgical options]] | [[Vulvar cancer primary prevention|Primary prevention]]  | [[Vulvar cancer secondary prevention|Secondary prevention]] | [[Vulvar cancer cost-effectiveness of therapy|Financial costs]] | [[Vulvar cancer future or investigational therapies|Future therapies]]
== Signs and Symptoms ==
Typically a lesion is present in form of a lump or [[ulceration]], often associated with itching, irritation, sometimes local bleeding and discharge. Also [[dysuria]], [[dyspareunia]] and pain may be noted.  Because of modesty or embarrassment, symptoms may not be heeded in a timely fashion.
Melanomas tend to display the typical dark discoloration.
Adenocarcinoma can arise from the [[Bartholin gland]] and results in a lump that may be quite painful.


== Diagnosis ==
== Diagnosis ==

Revision as of 16:07, 20 January 2012

For patient information click here

Vulvar cancer
ICD-10 C51..9
ICD-9 184.4
DiseasesDB 14013
MedlinePlus 000902

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Pathophysiology

Epidemiology & Demographics

Risk Factors

Screening

Causes

Differentiating Vulvar cancer

Complications & Prognosis

Diagnosis

History and Symptoms | Physical Examination | Staging | Laboratory tests | Electrocardiogram | X Rays | CT | MRI Echocardiography or Ultrasound | Other images | Alternative diagnostics

Treatment

Medical therapy | Surgical options | Primary prevention | Secondary prevention | Financial costs | Future therapies

Diagnosis

Examination of the vulva is part of the gynecologic evaluation and may reveal ulceration, a lump, or a mass. A suspicious lesion needs to undergo a biopsy that generally can be performed in an office setting under local anesthesia. Small lesion can be excised under local anesthesia. Supplemental evaluation may include a chest X-ray, an IVP, cystoscopy and proctoscopy, as well as blood counts and metabolic assessment.

Etiology

The etiology of the cancer is unclear; however, some condition such as condyloma or squamous dysplasias may have preceded the cancer. Human papillomavirus (HPV) is suspected to be a possible risk factor in the etiology of vulvar cancer. Patients infected with HIV tend to be more susceptible to vulvar malignancy. Also, smokers tend to be at higher risk.

Treatment

Staging and treatment are generally handled by an oncologist familiar with gynecologic cancer. The extent of the surgery is dictated by the surgical staging.[1]

Surgery is a mainstay of therapy and usually accomplished by use of a radical vulvectomy, removal of vulvar tissue as well as the removal of lymph nodes from the inguinal and femoral areas. Complications of such surgery include wound infection, sexual dysfunction, edema and thrombosis.

Surgery is significantly more extensive when vulvar cancer has spread to adjacent organs such as urethra, vagina, and rectum. In cases of early vulvar carcinoma the surgery may be less radical and disfiguring and consist of wide excision or a simple vulvectomy.

Radiation therapy and chemotherapy are usually not a primary choice of therapy but may be used in selected cases of advanced vulvar cancer.

Prognosis

The prognosis of vulvar cancer shows overall about a 75% five year survival rate, but, of course, individually affected by many factors, notably stage and type of the lesion and age and general medical health. Five-year survival is down to about 20% when pelvic lymph nodes are involved but better than 90% for patients with stage I lesions. Thus early diagnosis is imperative.

Help and Support

There is a support group for women who have/had vulva cancer/other vulva problems called VACO (Vulva Awareness Campaign Organisation). The website address for this is vaco.co.uk. It's just as easy as checking breasts. Women must check their vulva and to report any problems to their doctor as soon as possible.

References

External links

  1. Information from the National Cancer Institute


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