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| ==[[Paraganglioma history and symptoms|History & Symptoms]]== | | ==[[Paraganglioma history and symptoms|History & Symptoms]]== |
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| '''For patient information click [[Paraganglioma (patient information)|here]]'''
| | ==[[Paraganglioma surgery|Surgery]]== |
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| {{Paraganglioma}}
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| {{CMG}}
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| ==Overview== | |
| A '''paraganglioma''' is a rare [[neoplasm]] that can be found in the abdomen, thorax, and in the head and neck region. They are usually considered [[benign]] and complete surgical removal results in cure. However, in about 3% of cases they are [[malignant]] and have the ability to [[metastasis|metastasize]]. Paragangliomas are still sometimes called '''glomus tumors''' (not to be confused with [[glomus tumor]]s of the skin) and '''chemodectomas''', but paraganglioma is the currently accepted and preferred term.
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| Paragangliomas arise from the [[glomus cell]]s, which are special [[chemoreceptor]]s located along blood vessels that have a role in regulating blood pressure and blood flow. The main concentration of glomus cells are found are in the [[carotid body]], located in the upper neck at the branching of the [[carotid artery|common carotid artery]], and the [[aortic body|aortic bodies]], located near the [[aorta|aortic arch]]. The glomus cells are a part of the paraganglion system composed of the extra-adrenal [[paraganglia]] of the [[autonomic nervous system]], derived from the embryonic [[neural crest]]. Thus, paragangliomas are a type of [[neuroendocrine tumor]], and are closely related to [[pheochromocytoma]]s. Although all paragangliomas contain neurosecretory granules, only about 1-3% have clinical evidence of oversecretion.
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| ==Surgery==
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| The main treatment modalities are surgery, [[embolization]] and [[radiotherapy]].
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| ==References== | |
| {{reflist|2}}
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| {{Epithelial neoplasms}}
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| [[sk:Paraganglióm]]
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| [[Category:Disease]]
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| [[Category:Types of cancer]]
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| [[Category:Oncology]]
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| [[Category:Mature chapter]]
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| ==References== | | ==References== |