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==[[Paraneoplastic syndrome history and symptoms|History & Symptoms]]==
==[[Paraneoplastic syndrome history and symptoms|History & Symptoms]]==
A particularly devastating form of paraneoplastic syndromes is a group of disorders classified as [[paraneoplastic neurological disorder]]s (PNDs).<ref>{{cite journal |author=Rees JH |title=Paraneoplastic syndromes: when to suspect, how to confirm, and how to manage |journal=J. Neurol. Neurosurg. Psychiatr. |volume=75 Suppl 2 |issue= |pages=ii43-50 |year=2004 |pmid=15146039 |doi=}}</ref> These paraneoplastic disorders affect the brain and central nervous system and they are degenerative. Symptoms of paraneoplastic neurological disorders include [[ataxia]] (difficulty with walking and balance), [[dizziness]], [[nystagmus]] (rapid uncontrolled eye movements), difficulty swallowing, loss of [[muscle tone]], loss of fine [[motor coordination]], slurred speech, memory loss, vision problems, sleep disturbances, [[dementia]], [[Seizure|seizures]], sensory loss in the limbs.


The most common cancers associated with paraneoplastic neurological disorders are [[breast cancer|breast]], [[ovarian cancer|ovarian]] and [[lung cancer]], but many other cancers have been linked to PNDs as well.
==[[Paraneoplastic syndrome medical therapy|Medical Therapy]]==
==[[Paraneoplastic syndrome medical therapy|Medical Therapy]]==
Treatment options include:
Treatment options include:

Revision as of 19:59, 20 January 2012

Paraneoplastic syndrome
DiseasesDB 2064
MeSH D010257

Paraneoplastic syndrome Microchapters

Patient Information

Overview

Classification

Endocrine
Musculocutaneous
Neurological
Hematological
Others

Causes

Differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Classification

History & Symptoms

Medical Therapy

Treatment options include:

  1. Therapies to eliminate the underlying cancer such as chemotherapy, radiation and surgery, and
  2. Therapies to reduce or slow neurological degeneration. Rapid diagnosis and treatment is critical for the patient to have the best chance of recovery. Since these disorders are relatively rare, few doctors have seen or treated PNDs. Therefore, it is important that PND patients consult with a specialist with experience in diagnosing and treating paraneoplastic neurological disorders.

Organizations

The International Paraneoplastic Association (IPA) is an organization dedicated to providing support and information to those affected by paraneoplastic neurological disorders.

References


External links

Template:Tumors

de:Paraneoplastisches Syndrom Template:WH Template:WikiDoc Sources

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