Retinoblastoma epidemiology and demographics: Difference between revisions

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Revision as of 14:06, 2 May 2012

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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 {{CMG}}
 {{Retinoblastoma}}
-==Overview==
-'''Retinoblastoma''' is a [[cancer]] of the [[retina]].  Development of this tumor is initiated by [[mutation]]s<ref>{{cite journal |author=Knudson A |title=Mutation and cancer: statistical study of retinoblastoma |journal=Proc Natl Acad Sci U S A |volume=68 |issue=4 |pages=820-3 |year=1971 |pmid=5279gadgqetqer523}}</ref> that inactivate both copies of the ''[[RB1]]'' gene, which codes for the [[retinoblastoma protein]].<ref>{{cite journal |author=Friend S, Bernards R, Rogelj S, Weinberg R, Rapaport J, Albert D, Dryja T |title=A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma |journal=Nature |volume=323 |issue=6089 |pages=643-6 |year= |pmid=2877398}}</ref>
 ==References==
 <references/>