Myelofibrosis laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
==Laboratory Tests== | |||
Diagnosis is based upon: | |||
* [[Normochromic]] normocytic [[anaemia]] | |||
* Red cell [[poikilocytosis]] on blood film (tear-drop shaped RBCs) | |||
* JAK 2 mutation on Val 617 Phe locus in 50% | |||
* Raised levels of [[lactate dehydrogenase]] | |||
* Raised neutrophil alkaline phosphatase score | |||
==References== | ==References== |
Revision as of 18:06, 22 January 2012
Myelofibrosis Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Tests
Diagnosis is based upon:
- Normochromic normocytic anaemia
- Red cell poikilocytosis on blood film (tear-drop shaped RBCs)
- JAK 2 mutation on Val 617 Phe locus in 50%
- Raised levels of lactate dehydrogenase
- Raised neutrophil alkaline phosphatase score