Myelodysplastic syndrome laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Abnormalities include: | Abnormalities include: | ||
* [[neutropenia]], [[anemia]] and [[thrombocytopenia]] (low cell counts of white and red blood cells, and platelets, respectively) | * [[neutropenia]], [[anemia]] and [[thrombocytopenia]] (low cell counts of white and red blood cells, and platelets, respectively) | ||
* abnormal granules in cells, abnormal nuclear shape and size | * abnormal granules in cells, abnormal nuclear shape and size | ||
* [[chromosome|chromosomal]] abnormalities, including [[chromosomal translocation]]s and abnormal chromosome number. | * [[chromosome|chromosomal]] abnormalities, including [[chromosomal translocation]]s and abnormal chromosome number. | ||
==Laboratory Tests== | |||
* [[Full blood count]] and examination of [[blood film]]. The [[blood film]] morphology can provide clues about [[hemolytic anemia]], clumping of the [[platelets]] leading to spurious [[thrombocytopenia]], or [[leukemia]]. | |||
* Blood tests to eliminate other common causes of [[cytopenias]], such as [[lupus]], [[hepatitis]], [[B12]], [[folate]], or other [[vitamin]] deficiencies, [[renal failure]] or [[heart failure]], [[HIV]], [[hemolytic anemia]], [[monoclonal gammopathy]]. Age-appropriate cancer screening should be considered for all [[anemic]] patients. | |||
==References== | ==References== | ||
Revision as of 19:21, 22 January 2012
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Myelodysplastic syndrome Microchapters |
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Differentiating Myelodysplastic syndrome from other Diseases |
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Diagnosis |
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Myelodysplastic syndrome laboratory findings On the Web |
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American Roentgen Ray Society Images of Myelodysplastic syndrome laboratory findings |
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Risk calculators and risk factors for Myelodysplastic syndrome laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Abnormalities include:
- neutropenia, anemia and thrombocytopenia (low cell counts of white and red blood cells, and platelets, respectively)
- abnormal granules in cells, abnormal nuclear shape and size
- chromosomal abnormalities, including chromosomal translocations and abnormal chromosome number.
Laboratory Tests
- Full blood count and examination of blood film. The blood film morphology can provide clues about hemolytic anemia, clumping of the platelets leading to spurious thrombocytopenia, or leukemia.
- Blood tests to eliminate other common causes of cytopenias, such as lupus, hepatitis, B12, folate, or other vitamin deficiencies, renal failure or heart failure, HIV, hemolytic anemia, monoclonal gammopathy. Age-appropriate cancer screening should be considered for all anemic patients.