Chlamydia infection: Difference between revisions

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==Treatment==
==Treatment==
[[Chlamydia infection medical therapy|Medical therapy]] | [[Chlamydia infection surgery|Surgical options]] | [[Chlamydia infection primary prevention|Primary prevention]]  | [[Chlamydia infection secondary prevention|Secondary prevention]] | [[Chlamydia infection cost-effectiveness of therapy|Financial costs]] | [[Chlamydia infection future or investigational therapies|Future therapies]]
[[Chlamydia infection medical therapy|Medical therapy]] | [[Chlamydia infection surgery|Surgical options]] | [[Chlamydia infection primary prevention|Primary prevention]]  | [[Chlamydia infection secondary prevention|Secondary prevention]] | [[Chlamydia infection cost-effectiveness of therapy|Financial costs]] | [[Chlamydia infection future or investigational therapies|Future therapies]]
== Treatment ==
[[Image:ChlamydiaTrachomatisEinschlusskörperchen.jpg|thumb|right|''Chlamydia trachomatis'' inclusion bodies (brown) in a McCoy cell culture.]]
''C. trachomatis'' infection can be effectively cured with [[antibiotic]]s once it is detected. Current [[Centers for Disease Control]] guidelines provide for the following treatments:
* [[Azithromycin]] 1 gram oral as a single dose, or
* [[Doxycycline]] 100 milligrams twice daily for seven days.
* [[Tetracycline]]
* [[Erythromycin]]
Untested Treatments
* [[Ciprofloxacin]] 500 milligrams twice daily for 3 days.  (Although this is not an approved method of treatment, as it is shown to be ineffective and may simply delay symptoms.)
[[β-lactams]] are not suitable drugs for the treatment of chlamydia. While they have the ability to halt growth of the organism (i.e. are microbistatic), these antibiotics do not eliminate the bacteria. Once treatment is stopped, the bacteria will begin to grow once more.  (See below for Persistence.)


== Diseases caused by ''Chlamydia trachomatis'' ==
== Diseases caused by ''Chlamydia trachomatis'' ==

Revision as of 20:32, 27 January 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Pathophysiology

Epidemiology & Demographics

Risk Factors

Screening

Causes

Differentiating Chlamydia infection

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History and Symptoms | Physical Examination | Staging | Laboratory tests | Electrocardiogram | X Rays | CT | MRI Echocardiography or Ultrasound | Other images | Alternative diagnostics

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Diseases caused by Chlamydia trachomatis

Conjunctivitis due to chlamydia.

Chlamydia trachomatis can cause the following conditions:

Recent genetic discoveries

Recent phylogenetic studies have revealed that chlamydia shares a common ancestor with modern plants, and retains unusual plant-like traits (both genetically and physiologically). In particular, the enzyme L,L-diaminopimelate aminotransferase, which is related to lysine production in plants, is also linked with the construction of chlamydia's cell wall. The genetic encoding for the enzymes is remarkably similar in plants and chlamydia, demonstrating a close common ancestry.[1] This unexpected discovery may help scientists develop new treatment avenues: if scientists could find a safe and effective inhibitor of L,L-diaminopimelate aminotransferase, they might have a highly effective and extremely specific new antibiotic against chlamydia.

References

  1. McCoy AJ, Adams NE, Hudson AO, Gilvarg C, Leustek T, Maurelli AT (2006). "L,L-diaminopimelate aminotransferase, a trans-kingdom enzyme shared by Chlamydia and plants for synthesis of diaminopimelate/lysine". Proc. Natl. Acad. Sci. U.S.A. 103 (47): 17909–14. doi:10.1073/pnas.0608643103. PMID 17093042.

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ar:كلاميديا da:Klamydia de:Chlamydien it:Infezioni da clamidia he:כלמידיה mk:Хламидија ms:Penyakit kelamin Chlamydia nl:Chlamydia no:Klamydia-infeksjon sl:Klamidioza fi:Klamydia sv:Klamydia ta:கிளமிடியா

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