Leishmaniasis overview: Difference between revisions
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==Overview== | ==Overview== | ||
Leishmaniasis is a [[disease]] caused by [[protozoan]] [[parasite]]s that belong to the genus ''[[Leishmania]]'' and is transmitted by the bite of certain species of sand fly, including flies in the genus ''[[Lutzomyia]]'' in the New World and ''[[Phlebotomus]]'' in the Old World. The disease was named in 1901 for the Scottish [[pathologist]] [[William Boog Leishman]]. | |||
Most forms of the disease are transmissible only from animals ([[zoonosis]]), but some can be spread between humans. Human infection is caused by about 21 of 30 species that infect mammals. These include the ''L. donovani'' complex with three species (''L. donovani, L. infantum'', and'' L. chagasi''); the ''L. mexicana'' complex with 3 main species (''L. mexicana, L. amazonensis'', and ''L. venezuelensis''); ''L. tropica; L. major; L. aethiopica''; and the subgenus ''Viannia'' with four main species (''L. (V.) braziliensis, L. (V.) guyanensis, L. (V.) panamensis'', and ''L. (V.) peruviana''). The different species are morphologically indistinguishable, but they can be differentiated by [[isoenzyme]] analysis, DNA sequence analysis, or monoclonal antibodies. | Most forms of the disease are transmissible only from animals ([[zoonosis]]), but some can be spread between humans. Human infection is caused by about 21 of 30 species that infect mammals. These include the ''L. donovani'' complex with three species (''L. donovani, L. infantum'', and'' L. chagasi''); the ''L. mexicana'' complex with 3 main species (''L. mexicana, L. amazonensis'', and ''L. venezuelensis''); ''L. tropica; L. major; L. aethiopica''; and the subgenus ''Viannia'' with four main species (''L. (V.) braziliensis, L. (V.) guyanensis, L. (V.) panamensis'', and ''L. (V.) peruviana''). The different species are morphologically indistinguishable, but they can be differentiated by [[isoenzyme]] analysis, DNA sequence analysis, or monoclonal antibodies. | ||
[[Visceral leishmaniasis]] is a severe form in which the parasites have migrated to the vital organs. | [[Visceral leishmaniasis]] is a severe form in which the parasites have migrated to the vital organs. | ||
==References== | ==References== | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
[[Category:Parasitic diseases]] | [[Category:Parasitic diseases]] | ||
[[Category:Tropical disease]] | [[Category:Tropical disease]] | ||
[[Category:Insect-borne diseases]] | [[Category:Insect-borne diseases]] | ||
[[Category:Zoonoses]] | |||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} |
Revision as of 17:52, 9 December 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Leishmaniasis is a disease caused by protozoan parasites that belong to the genus Leishmania and is transmitted by the bite of certain species of sand fly, including flies in the genus Lutzomyia in the New World and Phlebotomus in the Old World. The disease was named in 1901 for the Scottish pathologist William Boog Leishman.
Most forms of the disease are transmissible only from animals (zoonosis), but some can be spread between humans. Human infection is caused by about 21 of 30 species that infect mammals. These include the L. donovani complex with three species (L. donovani, L. infantum, and L. chagasi); the L. mexicana complex with 3 main species (L. mexicana, L. amazonensis, and L. venezuelensis); L. tropica; L. major; L. aethiopica; and the subgenus Viannia with four main species (L. (V.) braziliensis, L. (V.) guyanensis, L. (V.) panamensis, and L. (V.) peruviana). The different species are morphologically indistinguishable, but they can be differentiated by isoenzyme analysis, DNA sequence analysis, or monoclonal antibodies.
Visceral leishmaniasis is a severe form in which the parasites have migrated to the vital organs.