Lyme disease causes: Difference between revisions
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==Overview== | ==Overview== | ||
==Cause== | |||
{{main|Lyme disease microbiology}} | |||
Lyme disease is caused by [[Gram-negative]] [[spirochetal]] [[bacteria]] from the [[genus]] ''[[Borrelia]]''. At least 37 ''Borrelia'' species have been described, 12 of which are Lyme related. The ''Borrelia'' [[species]] known to cause Lyme disease are collectively known as ''Borrelia burgdorferi'' sensu lato, and have been found to have greater [[genetic diversity|strain diversity]] than previously estimated.<ref name="Bunikis-a">{{cite journal | author=Bunikis J, Garpmo U, Tsao J, Berglund J, Fish D, Barbour AG | title=Sequence typing reveals extensive strain diversity of the Lyme borreliosis agents ''Borrelia burgdorferi'' in North America and ''Borrelia afzelii'' in Europe | journal=Microbiology | year=2004 | pages=1741-55 | volume=150 | issue=Pt 6 | pmid= 15184561 | url=http://mic.sgmjournals.org/cgi/reprint/150/6/1741.pdf | format=PDF}}</ref> | |||
Until recently it was thought that only three genospecies caused Lyme disease: ''B. burgdorferi'' sensu stricto (predominant in North America, but also in Europe), ''B. afzelii'', and ''B. garinii'' (both predominant in Eurasia). However, newly discovered genospecies have also been found to cause disease in humans. | |||
==References== | ==References== | ||
Revision as of 19:22, 8 February 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Cause
Lyme disease is caused by Gram-negative spirochetal bacteria from the genus Borrelia. At least 37 Borrelia species have been described, 12 of which are Lyme related. The Borrelia species known to cause Lyme disease are collectively known as Borrelia burgdorferi sensu lato, and have been found to have greater strain diversity than previously estimated.[1]
Until recently it was thought that only three genospecies caused Lyme disease: B. burgdorferi sensu stricto (predominant in North America, but also in Europe), B. afzelii, and B. garinii (both predominant in Eurasia). However, newly discovered genospecies have also been found to cause disease in humans.
References
- ↑ Bunikis J, Garpmo U, Tsao J, Berglund J, Fish D, Barbour AG (2004). "Sequence typing reveals extensive strain diversity of the Lyme borreliosis agents Borrelia burgdorferi in North America and Borrelia afzelii in Europe" (PDF). Microbiology. 150 (Pt 6): 1741–55. PMID 15184561.