Mononucleosis natural history: Difference between revisions
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==Overview== | ==Overview== | ||
== Risk Stratification and Prognosis== | |||
=== Complications === | |||
* '''Heme''' | |||
*:* [[Autoimmune hemolytic anemia]] | |||
*:* [[Thrombocytopenia]] | |||
*:* [[Granulocytopenia]] | |||
*:* Splenic rupture | |||
* '''Neuro''' | |||
*:* Cranial nerve palsies (Bell’s palsy) | |||
*:* [[Encephalitis]] | |||
* '''Liver''' | |||
*:* [[Hepatitis]] | |||
* '''Cardiac''' | |||
*:* [[Pericarditis]] | |||
*:* [[Myocarditis]] | |||
* '''Respiratory''' | |||
*:* Airway obstruction ([[adenopathy]]) | |||
Fatalities from mononucleosis are near impossible in developed nations. | |||
Uncommon, nonfatal complications exist, including various forms of CNS and hematological affection: | |||
*CNS: [[Meningitis]], [[encephalitis]], [[hemiplegia]] and transverse [[myelitis]]. EBV infection has also been proposed as a risk factor for the development of [[multiple sclerosis]] (MS)<ref>{{cite journal |author=Ascherio A, Munger KL |title=Environmental risk factors for multiple sclerosis. Part I: the role of infection |journal=Ann. Neurol. |volume=61 |issue=4 |pages=288–99 |year=2007 |pmid=17444504 |doi=10.1002/ana.21117}}</ref>, but this has not been affirmed. | |||
* Hematologic: EBV can cause [[autoimmune hemolytic anemia]] (direct [[Coombs test]] is positive) and various [[cytopenia]]s. | |||
==References== | ==References== | ||
Revision as of 21:47, 8 February 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Risk Stratification and Prognosis
Complications
- Heme
- Autoimmune hemolytic anemia
- Thrombocytopenia
- Granulocytopenia
- Splenic rupture
- Neuro
- Cranial nerve palsies (Bell’s palsy)
- Encephalitis
- Liver
- Cardiac
- Respiratory
- Airway obstruction (adenopathy)
Fatalities from mononucleosis are near impossible in developed nations.
Uncommon, nonfatal complications exist, including various forms of CNS and hematological affection:
- CNS: Meningitis, encephalitis, hemiplegia and transverse myelitis. EBV infection has also been proposed as a risk factor for the development of multiple sclerosis (MS)[1], but this has not been affirmed.
- Hematologic: EBV can cause autoimmune hemolytic anemia (direct Coombs test is positive) and various cytopenias.
References
- ↑ Ascherio A, Munger KL (2007). "Environmental risk factors for multiple sclerosis. Part I: the role of infection". Ann. Neurol. 61 (4): 288–99. doi:10.1002/ana.21117. PMID 17444504.