Botulism pathophysiology: Difference between revisions

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==Images==
==Images==


[[Image:Botulism outbreak.jpg|500px|This is a close up of contaminated Jalapeño peppers involved in an outbreak of botulism in Pontiac, Michigan, April, 1977. Ingestion of botulinal toxin results in an illness of variable severity. Common symptoms are diplopia, blurred vision, and bulbar weakness. Symmetric paralysis may progress rapidly.]]
[[Image:Botulism outbreak.jpg|400px|This is a close up of contaminated Jalapeño peppers involved in an outbreak of botulism in Pontiac, Michigan, April, 1977. Ingestion of botulinal toxin results in an illness of variable severity. Common symptoms are diplopia, blurred vision, and bulbar weakness. Symmetric paralysis may progress rapidly.]]


[[Image:Botulism type E.jpg|500pc|These are Clostridium botulinum Type E colonies displaying an opaque zone grown on a 48hr egg yolk agar plate; Mag. 1.9
[[Image:Botulism type E.jpg|400px|These are Clostridium botulinum Type E colonies displaying an opaque zone grown on a 48hr egg yolk agar plate; Mag. 1.9


C. botulinum Type E is an indigenous organism in the aquatic environment, and is the type mainly associated with botulism from seafood products. It is a Gram-positive, anaerobic, spore-forming food borne pathogen.]]
C. botulinum Type E is an indigenous organism in the aquatic environment, and is the type mainly associated with botulism from seafood products. It is a Gram-positive, anaerobic, spore-forming food borne pathogen.]]


[[Image:Botulism type A.jpg|500px|This Gram-stained micrograph of Clostridium botulinum Type-A in thioglycollate broth was incubated for 48hrs at 35°C
[[Image:Botulism type A.jpg|400px|This Gram-stained micrograph of Clostridium botulinum Type-A in thioglycollate broth was incubated for 48hrs at 35°C


C. botulinum is the bacterium responsible for the condition known as botulism, producing a neurotoxin the effects of which may be neutralized by various therapeutic agents.]]
C. botulinum is the bacterium responsible for the condition known as botulism, producing a neurotoxin the effects of which may be neutralized by various therapeutic agents.]]


[[Image:Botulism 2 type A.jpg|500px|This is a Clostridium botulinum type A colony grown on a 72 hour blood agar plate; Magnification 5X. The bacterium C. botulinum produces a nerve toxin, which causes the rare, but serious paralytic illness Botulism. There are seven types of botulism toxin designated by the letters A through G; only types A, B, E and F cause illness in humans.]]
[[Image:Botulism 2 type A.jpg|400px|This is a Clostridium botulinum type A colony grown on a 72 hour blood agar plate; Magnification 5X. The bacterium C. botulinum produces a nerve toxin, which causes the rare, but serious paralytic illness Botulism. There are seven types of botulism toxin designated by the letters A through G; only types A, B, E and F cause illness in humans.]]


[[Image:Botulism 3 type A.jpg|500px|These are Clostridium botulinum Type A colonies, Strain 2, grown on a 48hr blood agar plate.  The bacterium C. botulinum produces a nerve toxin, which causes the rare, but serious paralytic illness Botulism. There are seven types of botulism toxin designated by the letters A through G; only types A, B, E and F cause illness in humans.]]
[[Image:Botulism 3 type A.jpg|400px|These are Clostridium botulinum Type A colonies, Strain 2, grown on a 48hr blood agar plate.  The bacterium C. botulinum produces a nerve toxin, which causes the rare, but serious paralytic illness Botulism. There are seven types of botulism toxin designated by the letters A through G; only types A, B, E and F cause illness in humans.]]


[[Image:Botulism wound.jpg|500px|Wound botulism involvement of compound fracture of right arm.  14-year-old boy fractured his right ulna and radius and subsequently developed wound botulism.]]
[[Image:Botulism wound.jpg|400px|Wound botulism involvement of compound fracture of right arm.  14-year-old boy fractured his right ulna and radius and subsequently developed wound botulism.]]


[[Image:Botulism infant.jpg|500px|Six week old infant with botulism. Six week old infant with botulism, which is evident as a marked loss of muscle tone, especially in the region of the head and neck.]]
[[Image:Botulism infant.jpg|400px|Six week old infant with botulism. Six week old infant with botulism, which is evident as a marked loss of muscle tone, especially in the region of the head and neck.]]


[[Image:Botulism spores.jpg|500px|Clostridium botulinum spores stained with Malachite Green Stain.  The endospores of C. botulinum when stained using the Malachite Green staining method will appear as green spheres, while the bacilli themselves will turn purple in color.]]
[[Image:Botulism spores.jpg|400px|Clostridium botulinum spores stained with Malachite Green Stain.  The endospores of C. botulinum when stained using the Malachite Green staining method will appear as green spheres, while the bacilli themselves will turn purple in color.]]


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 15:48, 16 February 2012