Hepatitis C natural history: Difference between revisions
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==Natural History== | ==Natural History== | ||
Of every 100 people infected with the Hepatitis C virus, about | Of every 100 people infected with the Hepatitis C virus, about | ||
Revision as of 15:35, 5 April 2012
Natural History
Of every 100 people infected with the Hepatitis C virus, about
- 75–85 people will develop chronic Hepatitis C virus infection; of those,
- 60–70 people will go on to develop chronic liver disease
- 5–20 people will go on to develop cirrhosis over a period of 20–30 years
- 1–5 people will die from cirrhosis or liver cancer
Complications
- Hepatitis C infection can continue over many years leading to chronic hepatitis
- Over years, liver may undergo extensive damage and scarring resulting in cirrhosis
- Liver failure
- Hepatocellular carcinoma may occur in patients with chronic hepatitis C infection.[1]
Prognosis
- Acute Infection
- 20% recover
- 80% have persistent infection
- 30% of these patients develop cirrhosis
- Genotype
- Predicts response to treatment
- Genotype 1 less responsive than types 2 & 3
References
- ↑ Nash KL, Woodall T, Brown AS, Davies SE, Alexander GJ (2010). "Hepatocellular carcinoma in patients with chronic hepatitis C virus infection without cirrhosis". World Journal of Gastroenterology : WJG. 16 (32): 4061–5. PMC 2928460. PMID 20731020. Retrieved 2012-02-26. Unknown parameter
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