Alagille syndrome history and symptoms: Difference between revisions
m Robot: Changing Category:Mature chapter to Category:Overview complete |
|||
| Line 7: | Line 7: | ||
==Symptoms== | ==Symptoms== | ||
The most common symptom of Alagille syndrome is itching. | The most common symptom of Alagille syndrome is itching. | ||
The severity of the disorder can vary within the same family, with symptoms ranging from so mild as to go unnoticed to severe heart and/or liver disease requiring transplantation. The major clinical feature is due to cholestasis, due to bile duct paucity as seen on liver biopsy. Congenital heart defect, mostly pulmonary stenosis, typical facial features, skeletal features and posterior embryotoxon in the eye are commonly found. Renal and central nervous system abnormalities may occur. | |||
==References== | ==References== | ||
Revision as of 15:52, 24 July 2012
|
Alagille syndrome Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Alagille syndrome history and symptoms On the Web |
|
American Roentgen Ray Society Images of Alagille syndrome history and symptoms |
|
Risk calculators and risk factors for Alagille syndrome history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Alagille syndrome is a multisystem genetic disorder that affects the liver, heart, eyes,face, skeleton, kidneys and vascular system.
Symptoms
The most common symptom of Alagille syndrome is itching.
The severity of the disorder can vary within the same family, with symptoms ranging from so mild as to go unnoticed to severe heart and/or liver disease requiring transplantation. The major clinical feature is due to cholestasis, due to bile duct paucity as seen on liver biopsy. Congenital heart defect, mostly pulmonary stenosis, typical facial features, skeletal features and posterior embryotoxon in the eye are commonly found. Renal and central nervous system abnormalities may occur.