Retinoblastoma MRI: Difference between revisions
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==MRI== | ==MRI== | ||
'''High-resolution contrast enhanced MRI''' is the diagnostic technique of choice and should be used whenever possible to answer the key clinical questions. It has been proved to be the '''most sensitive technique''' for evaluating retinoblastoma | '''High-resolution contrast enhanced MRI''' is the diagnostic technique of choice and should be used whenever possible to answer the key clinical questions. It has been proved to be the '''most sensitive technique''' for evaluating retinoblastoma<ref name="pmid21850471">{{cite journal |author=de Graaf P, Göricke S, Rodjan F, Galluzzi P, Maeder P, Castelijns JA, Brisse HJ |title=Guidelines for imaging retinoblastoma: imaging principles and MRI standardization |journal=[[Pediatric Radiology]] |volume=42 |issue=1 |pages=2–14 |year=2012 |month=January |pmid=21850471 |pmc=3256324 |doi=10.1007/s00247-011-2201-5 |url=http://dx.doi.org/10.1007/s00247-011-2201-5 |accessdate=2012-05-29}}</ref> especially regarding tumor infiltration of the optic nerve, extraocular extension and intracranial disease. The 3D-multiplanar capability provide detailed examination of tumors and retrobulbar and intracranial structures. The tumor appears as '''heterogenously enhancing soft tissue mass with various degrees of calcification'''.<ref name="pmid10915702">{{cite journal |author=Kaste SC, Jenkins JJ, Pratt CB, Langston JW, Haik BG |title=Retinoblastoma: sonographic findings with pathologic correlation in pediatric patients |journal=[[AJR. American Journal of Roentgenology]] |volume=175 |issue=2 |pages=495–501 |year=2000 |month=August |pmid=10915702 |doi= |url=http://www.ajronline.org/cgi/pmidlookup?view=long&pmid=10915702 |accessdate=2012-05-29}}</ref> Lesions are typically hyperintense to vitreous on T1-weighted sequences and hypointense to vitreous on T2-weighted sequences.<ref name="pmid9884691">{{cite journal |author=Kaufman LM, Mafee MF, Song CD |title=Retinoblastoma and simulating lesions. Role of CT, MR imaging and use of Gd-DTPA contrast enhancement |journal=[[Radiologic Clinics of North America]] |volume=36 |issue=6 |pages=1101–17 |year=1998 |month=November |pmid=9884691 |doi= |url= |accessdate=2012-05-29}}</ref> | ||
==References== | ==References== | ||
Revision as of 19:44, 29 May 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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MRI
High-resolution contrast enhanced MRI is the diagnostic technique of choice and should be used whenever possible to answer the key clinical questions. It has been proved to be the most sensitive technique for evaluating retinoblastoma[1] especially regarding tumor infiltration of the optic nerve, extraocular extension and intracranial disease. The 3D-multiplanar capability provide detailed examination of tumors and retrobulbar and intracranial structures. The tumor appears as heterogenously enhancing soft tissue mass with various degrees of calcification.[2] Lesions are typically hyperintense to vitreous on T1-weighted sequences and hypointense to vitreous on T2-weighted sequences.[3]
References
- ↑ de Graaf P, Göricke S, Rodjan F, Galluzzi P, Maeder P, Castelijns JA, Brisse HJ (2012). "Guidelines for imaging retinoblastoma: imaging principles and MRI standardization". Pediatric Radiology. 42 (1): 2–14. doi:10.1007/s00247-011-2201-5. PMC 3256324. PMID 21850471. Retrieved 2012-05-29. Unknown parameter
|month=ignored (help) - ↑ Kaste SC, Jenkins JJ, Pratt CB, Langston JW, Haik BG (2000). "Retinoblastoma: sonographic findings with pathologic correlation in pediatric patients". AJR. American Journal of Roentgenology. 175 (2): 495–501. PMID 10915702. Retrieved 2012-05-29. Unknown parameter
|month=ignored (help) - ↑ Kaufman LM, Mafee MF, Song CD (1998). "Retinoblastoma and simulating lesions. Role of CT, MR imaging and use of Gd-DTPA contrast enhancement". Radiologic Clinics of North America. 36 (6): 1101–17. PMID 9884691. Unknown parameter
|month=ignored (help);|access-date=requires|url=(help)