Osteoporosis differential diagnosis: Difference between revisions
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* '''[[Idiopathic transient osteoporosis of hip]]''' - seen most often in women during the third trimester of pregnancy and in middle aged men. Complaints include groin pain and mild limited range of movements at the hip. X-ray shows diffuse [[osteopenia]] of the femoral head and neck. Treatment includes joint protection, limited weight bearing and [[NSAID]]s. Spontaneous recovery occurs after 2-9 months of conservative treatment. In pregnant women symptoms resolve in the first few months post-partum. | * '''[[Idiopathic transient osteoporosis of hip]]''' - seen most often in women during the third trimester of pregnancy and in middle aged men. Complaints include groin pain and mild limited range of movements at the hip. X-ray shows diffuse [[osteopenia]] of the femoral head and neck. Treatment includes joint protection, limited weight bearing and [[NSAID]]s. Spontaneous recovery occurs after 2-9 months of conservative treatment. In pregnant women symptoms resolve in the first few months post-partum. | ||
* '''[[Osteomalacia]]''' - caused by deficiency of [[vitamin D]] in adults. There is defective mineralization of newly formed bone. Diffuse bone pain, fatigue and fractures are the common symptoms. can progress to [[Osteoporosis]]. | * '''[[Osteomalacia]]''' - caused by deficiency of [[vitamin D]] in adults. There is defective mineralization of newly formed bone. Diffuse bone pain, fatigue and fractures are the common symptoms. can progress to [[Osteoporosis]]. | ||
* '''[[Scurvy]]''' - the biosynthesis of collagen is defective due to [[vitamiin C]] deficiency. New bone formation is prevented and the old bone becomes brittle due to lack and poor quality of collagen. Treatment is vitamin C replacement. | * '''[[Scurvy]]''' - the biosynthesis of collagen is defective due to [[vitamiin C]] deficiency. New bone formation is prevented and the old bone becomes brittle due to lack and poor quality of collagen. Treatment is vitamin C replacement. | ||
* '''[[Osteogenesis imperfecta]]''' - caused by defect in collagen and improper functioning of osteoblasts. Short stature, [[scoliosis]], tooth defects, hearing defects and propensity for fractures are the main clinical features. | |||
==References== | ==References== |
Revision as of 17:30, 20 July 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Raviteja Guddeti, M.B.B.S.[3]
Overview
Osteoporosis is a disease of old age where the done turnover is affected leading to fractures. It must be distinguished from Idiopathic transient osteoporosis of hip, Osteomalacia, Scurvy, Osteogenesis imperfecta, Multiple myeloma, Homocystinuria, Hypermetabolic resorptive osteoporosis etc.
Distinguishing Disease from other Conditions
- Idiopathic transient osteoporosis of hip - seen most often in women during the third trimester of pregnancy and in middle aged men. Complaints include groin pain and mild limited range of movements at the hip. X-ray shows diffuse osteopenia of the femoral head and neck. Treatment includes joint protection, limited weight bearing and NSAIDs. Spontaneous recovery occurs after 2-9 months of conservative treatment. In pregnant women symptoms resolve in the first few months post-partum.
- Osteomalacia - caused by deficiency of vitamin D in adults. There is defective mineralization of newly formed bone. Diffuse bone pain, fatigue and fractures are the common symptoms. can progress to Osteoporosis.
- Scurvy - the biosynthesis of collagen is defective due to vitamiin C deficiency. New bone formation is prevented and the old bone becomes brittle due to lack and poor quality of collagen. Treatment is vitamin C replacement.
- Osteogenesis imperfecta - caused by defect in collagen and improper functioning of osteoblasts. Short stature, scoliosis, tooth defects, hearing defects and propensity for fractures are the main clinical features.
References