Cerebral venous sinus thrombosis risk factors: Difference between revisions
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Cerebral venous sinus thrombosis is more common in particular situations. 85% of patients have at least one of these risk factors:<ref name=Stam2005/> | Cerebral venous sinus thrombosis is more common in particular situations. 85% of patients have at least one of these risk factors:<ref name=Stam2005>{{cite journal |author=Stam J |title=Thrombosis of the cerebral veins and sinuses |journal=N. Engl. J. Med. |volume=352 |issue=17 |pages=1791–8 |year=2005 |pmid=15858188 |doi=10.1056/NEJMra042354}}</ref> | ||
* [[Thrombophilia]] (a tendency to develop blood clots due to abnormalities in [[coagulation]], e.g. deficiency of [[protein C]], [[protein S]], [[antithrombin]] or related problems) | * [[Thrombophilia]] (a tendency to develop blood clots due to abnormalities in [[coagulation]], e.g. deficiency of [[protein C]], [[protein S]], [[antithrombin]] or related problems) | ||
* [[Nephrotic syndrome]] (a kidney problem causing protein loss in the urine) | * [[Nephrotic syndrome]] (a kidney problem causing protein loss in the urine) | ||
Revision as of 16:51, 24 July 2012
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Cerebral venous sinus thrombosis is more common in particular situations. 85% of patients have at least one of these risk factors:[1]
- Thrombophilia (a tendency to develop blood clots due to abnormalities in coagulation, e.g. deficiency of protein C, protein S, antithrombin or related problems)
- Nephrotic syndrome (a kidney problem causing protein loss in the urine)
- Chronic inflammatory diseases (inflammatory bowel disease, lupus, Behçet's disease)
- Pregnancy and puerperium (the period after giving birth)
- Particular blood disorders, especially polycythemia vera and paroxysmal nocturnal hemoglobinuria
- Use of the contraceptive pill
- Meningitis and infections of the ear, nose and throat area (mastoiditis, sinusitis)
- Direct injury to the venous sinuses, and medical procedures in the area
Other less well understood situations that increase the risk for cerebral sinus thrombosis are hyperthyroidism[2] and myelodysplastic syndrome.[3]
References
- ↑ Stam J (2005). "Thrombosis of the cerebral veins and sinuses". N. Engl. J. Med. 352 (17): 1791–8. doi:10.1056/NEJMra042354. PMID 15858188.
- ↑ Dai A, Wasay M, Dubey N, Giglio P, Bakshi R (2000). "Superior sagittal sinus thrombosis secondary to hyperthyroidism". Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 9 (2): 89–90. doi:10.1053/jscd.2000.0090089. PMID 17895204.
- ↑ Finelli PF, Harrison RB, Uphoff DF (1998). "Myelodysplastic syndrome and sagittal sinus thrombosis". Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 7 (3): 211–2. PMID 17895084.