Obliterative portal venopathy: Difference between revisions
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* [[Clotting]] factor abnormalities | * [[Clotting]] factor abnormalities | ||
==Differentiating from other Diseases== | == Differentiating from other Diseases == | ||
Differential diagnosis from [[liver cirrhosis]] is crucial and may be difficult. A large liver biopsy specimen, together with expertise and awareness of the examiner, are requested for optimal diagnosis. | |||
== Epidemiology and Demographics == | == Epidemiology and Demographics == | ||
Revision as of 05:03, 6 August 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Hepatoportal sclerosis
Overview
Hepatoportal sclerosis (HPS) is a rare disorder characterized by sclerosis of the intrahepatic portal veins.
Pathophysiology
Pathology
Causes
- Exposure to toxic substances (arsenic or vinyl chloride)
- autoimmune and connective tissue diseases
- systemic or intra abdominal infections
- Clotting factor abnormalities
Differentiating from other Diseases
Differential diagnosis from liver cirrhosis is crucial and may be difficult. A large liver biopsy specimen, together with expertise and awareness of the examiner, are requested for optimal diagnosis.
Epidemiology and Demographics
The prevalence of this disease is unknown, and the distribution is worldwide, with many cases reported in Asia.
Age
The disease can occur at any age.
Gender
Both males and females are equally affected.