Psittacosis laboratory tests: Difference between revisions
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* A fourfold or greater increase in [[antibody]] titers are against the diagnosis of ''C. psittaci'' in blood samples combined with the probable course of the disease. | * A fourfold or greater increase in [[antibody]] titers are against the diagnosis of ''C. psittaci'' in blood samples combined with the probable course of the disease. | ||
==References== | ==References== |
Revision as of 19:03, 7 August 2012
Psittacosis Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Overview
Exposure history is paramout to diagnosis. Bloodwork shows leukopenia, thrombocytopenia and moderately elevated liver enzymes.
Laboratory Findings
Electrolyte and Biomarker Studies
- Leukocytosis
- Rise in ESR
- Rise in CRP
- Liver enzymes elevated
- Hyponatremia may be noticed
- Rise in blood urea levels
- Urinalysis may show proteinuria
Chest X Ray
- Lobar consolidation may be seen
- Infiltrates may be evidenced
CT Scan
- On high resolution CT , infiltrates may be nodular and surrounded by ground glass opacity.[1]
Biopsy
- Macroscopically they have patchy consolidation.
- Microscopically exudation and interstitial changes are seen.
- They are best seen with Giemsa stain as inclusions called Leventhal -Colle-Lillie bodies and can be seen within macrophages in BAL fluid.
Culture
- Microbiological cultures from respiratory secretions.
- It is tedious process and seldom done .
Serology
- A fourfold or greater increase in antibody titers are against the diagnosis of C. psittaci in blood samples combined with the probable course of the disease.