Antithrombin III deficiency

Antithrombin III deficiency
ICD-9	289.81
OMIM	107300
DiseasesDB	783
MeSH	D020152

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Antithrombin III deficiency is a rare hereditary disorder that generally comes to light when a patient suffers recurrent venous thrombosis and pulmonary embolism.

This was first described by Egeberg in 1965.

The patients are treated with anticoagulants or, more rarely, with antithrombin concentrate.

In renal failure, especially nephrotic syndrome, antithrombin is lost in the urine, leading to a higher activity of Factor II and Factor X and in increased tendency to thrombosis.

Related Chapters

• Antithrombin

External links

• Patient's pages on antithrombin

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