Bucladesine: Difference between revisions

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==Overview==
==Overview==
'''Bucladesine''' is a [[phosphodiesterase inhibitor]].
'''Bucladesine''' is a cyclic nucleotide derivative which mimics the action of endogenous [[Cyclic adenosine monophosphate|cAMP]] and is a [[phosphodiesterase inhibitor]].
 
Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations.
 
The [[neurite]] outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.  


{{Phosphodiesterase inhibitors}}
{{Phosphodiesterase inhibitors}}
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[[Category:Phosphodiesterase inhibitors]]
[[Category:Phosphodiesterase inhibitors]]
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]
[[Category:Drugs]]


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Revision as of 19:21, 24 July 2014

Bucladesine
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC18H23N5NaO8P
Molar mass491.368 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor.

Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations.

The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.

Template:Phosphodiesterase inhibitors Template:Cardiac stimulants excluding cardiac glycosides


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