Bunaftine: Difference between revisions

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Bunaftine
Clinical data
ATC code	C01BD03 (WHO) ;
Identifiers
	IUPAC name N-[2-(diethylamino)ethyl]-N-propylnaphthalene-1-carboxamide;
CAS Number	32421-46-8 ;
PubChem CID	36131;
ChemSpider	33233 ;
UNII	GH09PRQ3FU;
KEGG	D07428 ;
ChEMBL	ChEMBL2104200;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C21H30N2O
Molar mass	326.476 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C(N(CCCC)CCN(CC)CC)c2cccc1ccccc12;
	InChI InChI=1S/C21H30N2O/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20/h8-14H,4-7,15-17H2,1-3H3 ; Key:WWGZXRYELYWJBD-UHFFFAOYSA-N ;
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VisualWikitext

Revision as of 22:24, 23 July 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Bunaftine is an antiarrhythmic agent.^[1] It is classified in class III.^[2]

It is also spelled "bunaphtine".^[3]

References

↑ Ferro G, Chiariello M, Tari MG, Vigorito C, Ungaro B, Condorelli M (May 1983). "Intropic effects of several antiarrhythmic drugs". Jpn Heart J. 24 (3): 377–90. PMID 6876382.
↑ Fenici R, Marchei M, Bellocci F, Zecchi P (July 1977). "Effect of bunaphtine on right atrial repolarisation in man". Br Heart J. 39 (7): 787–94. doi:10.1136/hrt.39.7.787. PMC 483317. PMID 328029.
↑ Tamargo J (August 1980). "Electrophysiological effects of bunaphtine in guinea-pig ventricular fibers". Arch Int Pharmacodyn Ther. 246 (2): 224–36. PMID 7436628.

Template:Antiarrhythmic agents

[pmid6876382-1] Ferro G, Chiariello M, Tari MG, Vigorito C, Ungaro B, Condorelli M (May 1983). "Intropic effects of several antiarrhythmic drugs". Jpn Heart J. 24 (3): 377–90. PMID 6876382.

[pmid328029-2] Fenici R, Marchei M, Bellocci F, Zecchi P (July 1977). "Effect of bunaphtine on right atrial repolarisation in man". Br Heart J. 39 (7): 787–94. doi:10.1136/hrt.39.7.787. PMC 483317. PMID 328029.

[pmid7436628-3] Tamargo J (August 1980). "Electrophysiological effects of bunaphtine in guinea-pig ventricular fibers". Arch Int Pharmacodyn Ther. 246 (2): 224–36. PMID 7436628.

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
-__NOTOC__
+{{Drugbox
-{{drugbox |
+| verifiedrevid = 447613606
-| IUPAC_name = ''N''-butyl-''N''-(2-diethylaminoethyl)naphthalene-1-<br>carboxamide
+| IUPAC_name = ''N''-[2-(diethylamino)ethyl]-''N''-propylnaphthalene-1-carboxamide
 | image = Bunaftine_svg.png
+<!--Clinical data-->
+| tradename =
+| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
+| pregnancy_US = <!-- A / B            / C / D / X -->
+| pregnancy_category =
+| legal_AU = <!-- Unscheduled / S2 / S3 / S4  / S8 -->
+| legal_UK = <!-- GSL         / P       / POM / CD -->
+| legal_US = <!-- OTC                   / Rx-only  -->
+| legal_status =
+| routes_of_administration =
+<!--Pharmacokinetic data-->
+| bioavailability =
+| protein_bound =
+| metabolism =
+| elimination_half-life =
+| excretion =
+<!--Identifiers-->
+| CAS_number_Ref = {{cascite|correct|??}}
 | CAS_number = 32421-46-8
 | ATC_prefix = C01
 | ATC_suffix = BD03
 | PubChem = 36131
-| DrugBank =
+| ChEMBL = 2104200
-| C = 21 | H = 30 | N = 2 | O = 1
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| DrugBank =
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 33233
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = GH09PRQ3FU
+| KEGG_Ref = {{keggcite|correct|kegg}}
+| KEGG = D07428
+<!--Chemical data-->
+| C=21 | H=30 | N=2 | O=1
 | molecular_weight = 326.476 g/mol
-| bioavailability =
+| smiles = O=C(N(CCCC)CCN(CC)CC)c2cccc1ccccc12
-| protein_bound =
+| InChI = 1/C21H30N2O/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20/h8-14H,4-7,15-17H2,1-3H3
-| metabolism =
+| InChIKey = WWGZXRYELYWJBD-UHFFFAOYAK
-| elimination_half-life =
+| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
-| excretion =
+| StdInChI = 1S/C21H30N2O/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20/h8-14H,4-7,15-17H2,1-3H3
-| pregnancy_AU =  <!-- A / B1 / B2 / B3 / C / D / X -->
+| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
-| pregnancy_US =  <!-- A / B            / C / D / X -->
+| StdInChIKey = WWGZXRYELYWJBD-UHFFFAOYSA-N
-| pregnancy_category =
-| legal_AU =      <!-- Unscheduled / S2 / S3 / S4  / S8 -->
-| legal_UK =      <!-- GSL         / P       / POM / CD -->
-| legal_US =      <!-- OTC                   / Rx-only  -->
-| legal_status =
-| routes_of_administration =
 }}
+__NOTOC__
+{{SI}}
 {{CMG}}
+==Overview==
+'''Bunaftine''' is an [[antiarrhythmic agent]].<ref name="pmid6876382">{{cite journal |author=Ferro G, Chiariello M, Tari MG, Vigorito C, Ungaro B, Condorelli M |title=Intropic effects of several antiarrhythmic drugs |journal=Jpn Heart J |volume=24 |issue=3 |pages=377–90 |date=May 1983 |pmid=6876382 |doi= |url=}}</ref> It is classified in [[class III antiarrhythmic|class III]].<ref name="pmid328029">{{cite journal |author=Fenici R, Marchei M, Bellocci F, Zecchi P |title=Effect of bunaphtine on right atrial repolarisation in man |journal=Br Heart J |volume=39 |issue=7 |pages=787–94 |date=July 1977 |pmid=328029 |pmc=483317 |doi= 10.1136/hrt.39.7.787|url=http://heart.bmj.com/cgi/pmidlookup?view=long&pmid=328029}}</ref>
+It is also spelled "bunaphtine".<ref name="pmid7436628">{{cite journal |author=Tamargo J |title=Electrophysiological effects of bunaphtine in guinea-pig ventricular fibers |journal=Arch Int Pharmacodyn Ther |volume=246 |issue=2 |pages=224–36 |date=August 1980 |pmid=7436628 |doi= |url=}}</ref>
-'''Bunaftine''' is a class III [[antiarrhythmic agent]].
+==References==
+{{reflist|2}}
 {{Antiarrhythmic agents}}
 [[Category:Antiarrhythmic agents]]
-[[Category:Drugs]]
+[[Category:Cardiovascular Drugs]]
-{{WikiDoc Help Menu}}
+[[Category:Drug]]
-{{WikiDoc Sources}}

Clinical data

ATC code	C01BD03 (WHO)
Identifiers
IUPAC name N-[2-(diethylamino)ethyl]-N-propylnaphthalene-1-carboxamide
CAS Number	32421-46-8^Y
PubChem CID	36131
ChemSpider	33233^Y
UNII	GH09PRQ3FU
KEGG	D07428^Y
ChEMBL	ChEMBL2104200
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₁H₃₀N₂O
Molar mass	326.476 g/mol
3D model (JSmol)	Interactive image
SMILES O=C(N(CCCC)CCN(CC)CC)c2cccc1ccccc12
InChI InChI=1S/C21H30N2O/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20/h8-14H,4-7,15-17H2,1-3H3^Y Key:WWGZXRYELYWJBD-UHFFFAOYSA-N^Y
(verify)

Bunaftine: Difference between revisions

Revision as of 22:24, 23 July 2014

Overview

References

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