Cefoperazone: Difference between revisions

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{{drugbox
__NOTOC__
| IUPAC_name        = (6''R'',7''S'')-7-{[2-[(4-ethyl-2,3-dioxo-piperazine-1-<br>carbonyl)amino]-2-(4-hydroxyphenyl)acetyl}amino]-<br>3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-<br>1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
{{Cefoperazone}}
| image            = Cefoperazone.svg
{{CMG}};{{AE}}{{AK}}
| CAS_number        = 62893-19-0
| ATC_prefix        = J01
| ATC_suffix        = DD12
| ATC_supplemental  = {{ATC|J01|DD62}}
| PubChem          = 44185
| DrugBank          =
| C=25|H=27|N=9|O=8|S=2
| molecular_weight  = 645.67 g/mol
| bioavailability  =
| protein_bound    =
| metabolism        =
| elimination_half-life =
| excretion        =
| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      =  <!-- A / B            / C / D / X -->
| pregnancy_category= 
| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA          =  <!--            / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK          =  <!-- GSL        / P      / POM / CD / Class A, B, C -->
| legal_US          =  <!-- OTC                  / Rx-only  / Schedule I, II, III, IV, V -->
| legal_status      =
| routes_of_administration =
}}
 
{{SI}}


==Overview==
==Overview==
Line 32: Line 7:


''Cefina-SB'' is a combination of [[sulbactam]] and cefoperazone. Cefoperazone exerts its bactericidal effect by inhibiting the [[bacterial]] [[cell wall]] synthesis, and sulbactam acts as a beta-lactamase inhibitor, to increase the antibacterial activity of cefoperazone against beta-lactamase producing organisms. Cefina-SB is available as injection for the treatment of bacterial infections. In some countries, the combination is sold as ''Sulperazone''. Cefoperazone is available in the United States as Cefobid.
''Cefina-SB'' is a combination of [[sulbactam]] and cefoperazone. Cefoperazone exerts its bactericidal effect by inhibiting the [[bacterial]] [[cell wall]] synthesis, and sulbactam acts as a beta-lactamase inhibitor, to increase the antibacterial activity of cefoperazone against beta-lactamase producing organisms. Cefina-SB is available as injection for the treatment of bacterial infections. In some countries, the combination is sold as ''Sulperazone''. Cefoperazone is available in the United States as Cefobid.
==Category==
[[Cephalosporins]], third generation.
==US Brand Names==
CEFOBID<sup>®</sup>
==FDA Package Insert==
'''  [[cefoperazone description|Description]]'''
'''| [[cefoperazone clinical pharmacology|Clinical Pharmacology]]'''
'''| [[cefoperazone microbiology|Microbiology]]'''
'''| [[cefoperazone indications and usage|Indications and Usage]]'''
'''| [[cefoperazone contraindications|Contraindications]]'''
'''| [[cefoperazone warnings and precautions|Warnings and Precautions]]'''
'''| [[cefoperazone adverse reactions|Adverse Reactions]]'''
'''| [[cefoperazone overdosage|Overdosage]]'''
'''| [[cefoperazone clinical studies|Clinical Studies]]'''
'''| [[cefoperazone dosage and administration|Dosage and Administration]]'''
'''| [[cefoperazone Compatibility and Stability|Compatibility and Stability]]'''
'''| [[cefoperazone how supplied|How Supplied]]'''
'''| [[cefoperazone labels and packages|Labels and Packages]]'''




{{CephalosporinAntiBiotics}}
{{CephalosporinAntiBiotics}}


{{WH}}
{{WH}}
{{WS}}
{{WS}}
==References==
{{Reflist|2}}
http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c6c2ef3b-2c53-4737-9f7d-2d7e040c6e87
[[Category:Antibiotics]]
[[Category:Wikinfect]]

Revision as of 05:31, 7 January 2014

cefoperazone
Cefobid® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Dosage and Administration
Compatibility and Stability
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]

Overview

Cefoperazone is a third generation cephalosporin antibiotic. Marketed by pfizer under the name Cefobid®.

Cefina-SB is a combination of sulbactam and cefoperazone. Cefoperazone exerts its bactericidal effect by inhibiting the bacterial cell wall synthesis, and sulbactam acts as a beta-lactamase inhibitor, to increase the antibacterial activity of cefoperazone against beta-lactamase producing organisms. Cefina-SB is available as injection for the treatment of bacterial infections. In some countries, the combination is sold as Sulperazone. Cefoperazone is available in the United States as Cefobid.

Category

Cephalosporins, third generation.

US Brand Names

CEFOBID®

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Clinical Studies | Dosage and Administration | Compatibility and Stability | How Supplied | Labels and Packages



Template:WH Template:WS

References

http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c6c2ef3b-2c53-4737-9f7d-2d7e040c6e87

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