Colesevelam: Difference between revisions

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__NOTOC__
__NOTOC__
{{drugbox
{{Colesevelam}}
| IUPAC_name        =
{{CMG}}; {{AE}}  {{SS}}
| image            = Colesevelam.png
| CAS_number        =
| ATC_prefix        = C10
| ATC_suffix        = AC04
| PubChem          = 160051
| DrugBank          =
| chemical_formula  =
| C=31|H=67|C=l3|N=4|O=1
| molecular_weight  = 618.248 g/mol
| bioavailability  = n/a
| protein_bound    =
| metabolism        =  Not metabolized by the body, Colesevelam (trade name "Welchol") is not absorbed by the body.
| elimination_half-life = n/a (non-systemic drug)
| excretion        =  By intestines only, Colesevelam is 100% non-systemic
| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      =  <!-- A / B            / C / D / X -->
| pregnancy_category=  B
| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA          =  <!--            / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK          =  <!-- GSL        / P      / POM / CD / Class A, B, C -->
| legal_US          =  <!-- OTC                  / Rx-only  / Schedule I, II, III, IV, V -->
| legal_status      = Rx-only
| routes_of_administration =
}}
{{CMG}}


'''''For patient information about Colesevelam, click [[Colesevelam (patient information)|here]].'''''


{{SB}} WELCHOL<sup>®</sup>


==[[Colesevelam (patient information)|For patient information, click here]]==
==Overview==
'''Colesevelam''' is a [[bile acid sequestrant]] administered orally. It is developed by [[Genzyme]] and marketed in the US by Daiichi Sankyo under the brand name '''Welchol''' and elsewhere by Genzyme as '''Cholestagel'''.  In Canada it is marketed by Valeant as '''Lodalis'''.
 
==Category==
Cardiovasuclar Drugs:Bile acid sequestrants
 
==FDA Package Insert==
 
'''  [[Colesevelam indications and usage|Indications and Usage]]'''
'''| [[Colesevelam dosage and administration|Dosage and Administration]]'''
'''| [[Colesevelam dosage forms and strengths|Dosage Forms and Strengths]]'''
'''| [[Colesevelam contraindications|Contraindications]]'''
'''| [[Colesevelam warnings and precautions|Warnings and Precautions]]'''
'''| [[Colesevelam adverse reactions|Adverse Reactions]]'''
'''| [[Colesevelam drug interactions|Drug Interactions]]'''
'''| [[Colesevelam use in specific populations|Use in Specific Populations]]'''
'''| [[Colesevelam overdosage|Overdosage]]'''
'''| [[Colesevelam description|Description]]'''
'''| [[Colesevelam clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Colesevelam nonclinical toxicology|Nonclinical Toxicology]]'''
'''| [[Colesevelam clinical studies|Clinical Studies]]'''
'''| [[Colesevelam how supplied storage and handling|How Supplied/Storage and Handling]]'''
'''| [[Colesevelam patient counseling information|Patient Counseling Information]]'''
'''| [[Colesevelam labels and packages|Labels and Packages]]'''


==Overview==
==Mechanism of Action==
'''Colesevelam''' is a [[bile acid sequestrant]].


==References==


{{Reflist|2}}
{{Lipid modifying agents}}
{{Lipid modifying agents}}


[[Category:Hepatology]]
[[Category:Bile acid sequestrants]]
[[Category:Cardiovasuclar Drugs]]
[[Category:Drugs]]
[[Category:Drugs]]
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}

Revision as of 17:14, 10 February 2014

Colesevelam
Clinical data
Trade namesWelchol, Cholestagel
MedlinePlusa699050
Pregnancy
category
  • B
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityN/A
MetabolismColesevelam is not absorbed and not metabolised.
Elimination half-lifeN/A (non-systemic drug)
ExcretionBy intestines only, colesevelam is non-systemic.
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
 ☒N☑Y (what is this?)  (verify)

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]

For patient information about Colesevelam, click here.

Synonyms / Brand Names: WELCHOL®

Overview

Colesevelam is a bile acid sequestrant administered orally. It is developed by Genzyme and marketed in the US by Daiichi Sankyo under the brand name Welchol and elsewhere by Genzyme as Cholestagel. In Canada it is marketed by Valeant as Lodalis.

Category

Cardiovasuclar Drugs:Bile acid sequestrants

FDA Package Insert

Indications and Usage | Dosage and Administration | Dosage Forms and Strengths | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Use in Specific Populations | Overdosage | Description | Clinical Pharmacology | Nonclinical Toxicology | Clinical Studies | How Supplied/Storage and Handling | Patient Counseling Information | Labels and Packages

Mechanism of Action

References

Template:Lipid modifying agents

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