Drug allergy overview: Difference between revisions
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A '''drug allergy''' is an [[allergy]] to a [[drug]], most commonly a [[medication]]. Medical attention should be sought immediately if an allergic reaction is suspected.A drug induced fever is a state wherein the administration of [[Medication|drugs]] intended to help a patient, causes a fever. The drug may interfere with heat dissipation peripherally, increase the rate of [[metabolism]], evoke a cellular or humoral [[immune response]], mimic endogenous [[pyrogen]], or damage tissues. | A '''drug allergy''' is an [[allergy]] to a [[drug]], most commonly a [[medication]]. Medical attention should be sought immediately if an allergic reaction is suspected.A drug induced fever is a state wherein the administration of [[Medication|drugs]] intended to help a patient, causes a fever. The drug may interfere with heat dissipation peripherally, increase the rate of [[metabolism]], evoke a cellular or humoral [[immune response]], mimic endogenous [[pyrogen]], or damage tissues. | ||
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A drug allergy is different from an intolerance. A [[drug intolerance]], which is often a milder, non-immune-mediated reaction, does not depend on prior exposure. Most people who believe they are allergic to [[aspirin]] are actually suffering from a drug intolerance. | A drug allergy is different from an intolerance. A [[drug intolerance]], which is often a milder, non-immune-mediated reaction, does not depend on prior exposure. Most people who believe they are allergic to [[aspirin]] are actually suffering from a drug intolerance. | ||
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Revision as of 20:23, 14 August 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Charmaine Patel, M.D. [2]
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Overview
A drug allergy is an allergy to a drug, most commonly a medication. Medical attention should be sought immediately if an allergic reaction is suspected.A drug induced fever is a state wherein the administration of drugs intended to help a patient, causes a fever. The drug may interfere with heat dissipation peripherally, increase the rate of metabolism, evoke a cellular or humoral immune response, mimic endogenous pyrogen, or damage tissues.
An allergic reaction will not occur on the first exposure to a substance. The first exposure allows the body to create antibodies and memory lymphocyte cells for the antigen. However, drugs often contain many different substances, including dyes, which could cause allergic reactions. This can cause an allergic reaction on the first administration of a drug. For example, a person who developed an allergy to a red dye will be allergic to any new drug which contains that red dye.
A drug allergy is different from an intolerance. A drug intolerance, which is often a milder, non-immune-mediated reaction, does not depend on prior exposure. Most people who believe they are allergic to aspirin are actually suffering from a drug intolerance.