|
|
| Line 1: |
Line 1: |
| {{drugbox
| | #REDIRECT [[Terazosin#Pharmacology]] |
| | IUPAC_name = [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl) piperazin-1-yl]- tetrahydrofuran-2-yl-methanone
| |
| | image = Terazosin.svg
| |
| | CAS_number = 63590-64-7
| |
| | ATC_prefix = G04
| |
| | ATC_suffix = CA03
| |
| | ATC_supplemental =
| |
| | PubChem = 5401
| |
| | DrugBank = APRD00667
| |
| | C=19 | H=25 | N=5 | O=4
| |
| | molecular_weight = 387.433 g/mol
| |
| | bioavailability =
| |
| | protein_bound = 90-94%
| |
| | metabolism =
| |
| | elimination_half-life = 12 hours
| |
| | pregnancy_category =
| |
| | legal_status =
| |
| | routes_of_administration =
| |
| }}
| |
| | |
| | |
| '''Terazosin''' ('''Hytrin''') is a selective [[alpha 1 antagonist]] used for treatment of symptoms of an enlarged [[prostate]] ([[benign prostatic hyperplasia|BPH]]). It also acts to lower the [[blood pressure]], and is therefore a drug of choice for men with [[hypertension]] and prostate enlargement.
| |
| | |
| It works by blocking the action of [[adrenaline]] on [[smooth muscle]] of the [[urinary bladder|bladder]] and the [[blood vessel]] walls.
| |
| | |
| Most common side effects include dizziness, drowsiness, headache, constipation, loss of appetite, fatigue, nasal congestion or dry eyes, but they generally go away after only a few days of use. Therapy should always be started with a low dose to avoid [[first dose phenomenon]].<ref>[http://www.rxlist.com/cgi/generic/teraz_wcp.htm Hytrin (Terazosin Hcl) drug warnings and precautions - prescription drugs and medications at RxList<!-- Bot generated title -->]</ref> Sexual side effects are rare, but may include [[priapism]] or [[erectile dysfunction]].
| |
| | |
| ==References==
| |
| <references/>
| |
| | |
| {{Urologicals}}
| |
| | |
| [[Category:Alpha blockers]]
| |
| | |
| {{pharma-stub}}
| |
| | |
| [[fr:Térazosine]]
| |
| [[id:Terazosin]] | |
| {{WH}}
| |
| {{WS}}
| |