Vaginal discharge: Difference between revisions
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{{CMG}}; '''Associate Editor(s)-in-Chief:''' [[User: Shankar Kumar |Shankar Kumar, M.B.B.S.]] [mailto:kumarshankar@wikidoc.org]] | {{CMG}}; '''Associate Editor(s)-in-Chief:''' [[User: Shankar Kumar|Shankar Kumar, M.B.B.S.]] [mailto:kumarshankar@wikidoc.org]] | ||
== Overview == | |||
'''Vaginal discharge''' is a common patient complaint that is paired with anxiety regarding sexually transmitted diseases. If a STD is detected, a search for all other STDs should be done. Advise the infected patient to inform all sexual partners of their diagnosis. | '''Vaginal discharge''' is a common patient complaint that is paired with anxiety regarding sexually transmitted diseases. If a STD is detected, a search for all other STDs should be done. Advise the infected patient to inform all sexual partners of their diagnosis. | ||
===Common causes of Vaginal discharge=== | === Common causes of Vaginal discharge === | ||
*[[Bacterial vaginosis]] | * [[Bacterial vaginosis]] | ||
*[[Vaginal yeast infection]] | * [[Vaginal yeast infection]] | ||
*[[Trichomoniasis]] | * [[Trichomoniasis]] | ||
*[[Chlamydia]] | * [[Chlamydia]] | ||
*[[Gonorrhea]] | * [[Gonorrhea]] | ||
*[[Herpes]] | * [[Herpes]] | ||
*[[Foreign body vaginitis]] | * [[Foreign body vaginitis]] | ||
*[[Atrophic vaginitis]] | * [[Atrophic vaginitis]] | ||
*[[cervical cancer]] | * [[cervical cancer]] | ||
*[[Vaginal cancer]] | * [[Vaginal cancer]] | ||
=== Complete Differential Diagnosis of the Causes of Vaginal discharge === | |||
(By organ system) | |||
{| style="width:80%; height:100px" border="1" | |||
| style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | |||
{|style="width:80%; height:100px" border="1" | | style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes | ||
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | |||
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes | |||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Chemical / poisoning''' | | '''Chemical / poisoning''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Dermatologic''' | | '''Dermatologic''' | ||
|bgcolor="Beige"| [[Scabies]] | | bgcolor="Beige"| [[Scabies]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Drug Side Effect''' | | '''Drug Side Effect''' | ||
|bgcolor="Beige"| [[Amoxicillin and Clavulanic Acid ]], [[Butoconazole Vaginal Cream ]], [[Clotrimazole ]], [[Combined oral contraceptive pill]], [[Estradiol Topical ]], [[Estradiol Transdermal ]], [[Estrogen and Progestin (Oral Contraceptives) ]],[[Estrogen Injection ]], [[Estrogen Vaginal ]], [[Etonogestrel and Ethinyl Estradiol Vaginal Ring ]], [[Glatiramer Injection ]],[[Hormone replacement therapy (trans)]], [[Leuprolide ]], [[Medroxyprogesterone Injection ]], [[Metronidazole Topical ]],[[Miconazole ]], [[Nafarelin ]], [[Natalizumab injection ]], [[Norelgestromin and ethinyl estradiol transdermal system ]],[[Oxcarbazepine ]], [[Tamoxifen ]], [[Terconazole Vaginal Cream, Vaginal Suppositories ]], [[Zoledronic Acid Injection ]] | | bgcolor="Beige"| [[Amoxicillin and Clavulanic Acid ]], [[Butoconazole Vaginal Cream ]], [[Clotrimazole ]], [[Combined oral contraceptive pill]], [[Estradiol Topical ]], [[Estradiol Transdermal ]], [[Estrogen and Progestin (Oral Contraceptives) ]],[[Estrogen Injection ]], [[Estrogen Vaginal ]], [[Etonogestrel and Ethinyl Estradiol Vaginal Ring ]], [[Glatiramer Injection ]],[[Hormone replacement therapy (trans)]], [[Leuprolide ]], [[Medroxyprogesterone Injection ]], [[Metronidazole Topical ]],[[Miconazole ]], [[Nafarelin ]], [[Natalizumab injection ]], [[Norelgestromin and ethinyl estradiol transdermal system ]],[[Oxcarbazepine ]], [[Tamoxifen ]], [[Terconazole Vaginal Cream, Vaginal Suppositories ]], [[Zoledronic Acid Injection ]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Ear Nose Throat''' | | '''Ear Nose Throat''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Endocrine''' | | '''Endocrine''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Environmental''' | | '''Environmental''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Gastroenterologic''' | | '''Gastroenterologic''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Genetic''' | | '''Genetic''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Hematologic''' | | '''Hematologic''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Iatrogenic''' | | '''Iatrogenic''' | ||
|bgcolor="Beige"| [[Colposcopy]] | | bgcolor="Beige"| [[Colposcopy]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Infectious Disease''' | | '''Infectious Disease''' | ||
|bgcolor="Beige"| [[Pelvic inflammatory disease]], [[Urethritis]], [[Cervicitis]], [[Vaginitis]], [[Vulvitis]] | | bgcolor="Beige"| [[Pelvic inflammatory disease]], [[Urethritis]], [[Cervicitis]], [[Vaginitis]], [[Vulvitis]] | ||
<u>'''Bacteria'''</u>: | <u>'''Bacteria'''</u>: | ||
Line 109: | Line 109: | ||
[[Trichomonas vaginalis]], [[Trichomoniasis]] | [[Trichomonas vaginalis]], [[Trichomoniasis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Musculoskeletal / Ortho''' | | '''Musculoskeletal / Ortho''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Neurologic''' | | '''Neurologic''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Nutritional / Metabolic''' | | '''Nutritional / Metabolic''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Obstetric/Gynecologic''' | | '''Obstetric/Gynecologic''' | ||
|bgcolor="Beige"| [[Lochia]], [[Menstrual cycle]], [[Postnatal]], [[Pregnancy]] | | bgcolor="Beige"| [[Lochia]], [[Menstrual cycle]], [[Postnatal]], [[Pregnancy]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Oncologic''' | | '''Oncologic''' | ||
|bgcolor="Beige"| [[Cervical cancer]], [[Endometrial cancer]], [[Uterine sarcoma]], [[Vaginal cancer]] | | bgcolor="Beige"| [[Cervical cancer]], [[Endometrial cancer]], [[Uterine sarcoma]], [[Vaginal cancer]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Opthalmologic''' | | '''Opthalmologic''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Overdose / Toxicity''' | | '''Overdose / Toxicity''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Psychiatric''' | | '''Psychiatric''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Pulmonary''' | | '''Pulmonary''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Renal / Electrolyte''' | | '''Renal / Electrolyte''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Rheum / Immune / Allergy''' | | '''Rheum / Immune / Allergy''' | ||
|bgcolor="Beige"| [[Allergic vaginitis]] | | bgcolor="Beige"| [[Allergic vaginitis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Sexual''' | | '''Sexual''' | ||
|bgcolor="Beige"| [[Atrophic Vaginitis]], [[Cervical cancer]], [[Cervical polyp]], [[Cervicitis]], [[Endometrial cancer]], [[Foreign body vaginitis]], [[Salpingitis]], [[Uterine sarcoma]], [[Vaginal cancer]], [[Vaginitis]], [[Vesicovaginal fistula]], [[Vulvitis]],[[Colposcopy]], [[Pelvic inflammatory disease]], [[Allergic vaginitis]], [[Vaginal trauma]], [[Bacterial Vaginosis]],[[Candidiasis]] | | bgcolor="Beige"| [[Atrophic Vaginitis]], [[Cervical cancer]], [[Cervical polyp]], [[Cervicitis]], [[Endometrial cancer]], [[Foreign body vaginitis]], [[Salpingitis]], [[Uterine sarcoma]], [[Vaginal cancer]], [[Vaginitis]], [[Vesicovaginal fistula]], [[Vulvitis]],[[Colposcopy]], [[Pelvic inflammatory disease]], [[Allergic vaginitis]], [[Vaginal trauma]], [[Bacterial Vaginosis]],[[Candidiasis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Trauma''' | | '''Trauma''' | ||
|bgcolor="Beige"| [[Vaginal trauma]] | | bgcolor="Beige"| [[Vaginal trauma]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Urologic''' | | '''Urologic''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Dental''' | | '''Dental''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Miscellaneous''' | | '''Miscellaneous''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|} | |} | ||
=== Complete Differential Diagnosis of the Causes of Vaginal discharge === | |||
(In alphabetical order) | (In alphabetical order) | ||
{{MultiCol}} | {{MultiCol}} | ||
*[[ | * [[Allergic vaginitis]] | ||
*[[ | * [[Amoxicillin and Clavulanic Acid ]] | ||
*[[ | * [[Atrophic Vaginitis]] | ||
*[[ | * [[Bacterial Vaginosis]] | ||
*[[ | * [[Butoconazole Vaginal Cream ]] | ||
*[[ | * [[Candidiasis]] | ||
*[[Cervical | * [[Cervical cancer]] | ||
*[[ | * [[Cervical polyp]] | ||
*[[ | * [[Cervicitis]] | ||
*[[ | * [[Chlamydia]] | ||
*[[ | * [[Clotrimazole ]] | ||
*[[ | * [[Colposcopy]] | ||
*[[ | * [[Combined oral contraceptive pill]] | ||
*[[ | * [[Endometrial cancer]] | ||
*[[Estradiol | * [[Estradiol Topical ]] | ||
*[[ | * [[Estradiol Transdermal ]] | ||
*[[Estrogen | * [[Estrogen and Progestin (Oral Contraceptives) ]] | ||
*[[Estrogen | * [[Estrogen Injection ]] | ||
*[[ | * [[Estrogen Vaginal ]] | ||
*[[ | * [[Etonogestrel and Ethinyl Estradiol Vaginal Ring ]] | ||
*[[ | * [[Foreign body vaginitis]] | ||
*[[ | * [[Glatiramer Injection ]] | ||
*[[ | * [[Gonorrhea]] | ||
*[[ | * [[Herpes simplex]] | ||
*[[ | * [[HIV]] | ||
*[[Human Papillomavirus infections]] | * [[Hormone replacement therapy (trans)]] | ||
* [[Human Papillomavirus infections]] | |||
{{ColBreak}} | {{ColBreak}} | ||
*[[Leuprolide ]] | * [[Leuprolide ]] | ||
*[[Lochia]] | * [[Lochia]] | ||
*[[Medroxyprogesterone Injection ]] | * [[Medroxyprogesterone Injection ]] | ||
*[[Menstrual cycle]] | * [[Menstrual cycle]] | ||
*[[Metronidazole Topical ]] | * [[Metronidazole Topical ]] | ||
*[[Miconazole ]] | * [[Miconazole ]] | ||
*[[Nafarelin ]] | * [[Nafarelin ]] | ||
*[[Natalizumab injection ]] | * [[Natalizumab injection ]] | ||
*[[Norelgestromin and ethinyl estradiol transdermal system ]] | * [[Norelgestromin and ethinyl estradiol transdermal system ]] | ||
*[[Oxcarbazepine ]] | * [[Oxcarbazepine ]] | ||
*[[Pelvic inflammatory disease]] | * [[Pelvic inflammatory disease]] | ||
*[[Postnatal]] | * [[Postnatal]] | ||
*[[Pregnancy]] | * [[Pregnancy]] | ||
*[[Salpingitis]] | * [[Salpingitis]] | ||
*[[Scabies]] | * [[Scabies]] | ||
*[[Syphilis]] | * [[Syphilis]] | ||
*[[Tamoxifen ]] | * [[Tamoxifen ]] | ||
*[[Terconazole Vaginal Cream, Vaginal Suppositories ]] | * [[Terconazole Vaginal Cream, Vaginal Suppositories ]] | ||
*[[Trichomonas vaginalis]] | * [[Trichomonas vaginalis]] | ||
*[[Trichomoniasis]] | * [[Trichomoniasis]] | ||
*[[Urethritis]] | * [[Urethritis]] | ||
*[[Uterine sarcoma]] | * [[Uterine sarcoma]] | ||
*[[Vaginal cancer]] | * [[Vaginal cancer]] | ||
*[[Vaginal trauma]] | * [[Vaginal trauma]] | ||
*[[Vaginitis]] | * [[Vaginitis]] | ||
*[[Vesicovaginal fistula]] | * [[Vesicovaginal fistula]] | ||
*[[Vulvitis]] | * [[Vulvitis]] | ||
*[[Zoledronic Acid Injection ]] | * [[Zoledronic Acid Injection ]] | ||
{{EndMultiCol}} | {{EndMultiCol}} | ||
== Laboratory Findings == | == Laboratory Findings == | ||
Initial tests include: | Initial tests include: | ||
*[[CBC]] | |||
*[[urinalysis]] | * [[CBC]] | ||
*[[urine]] culture | * [[urinalysis]] | ||
*[[beta-hCG]] | * [[urine]] culture | ||
*[[gonorrhea]] culture | * [[beta-hCG]] | ||
*[[chlamydia]] culture | * [[gonorrhea]] culture | ||
* [[chlamydia]] culture | |||
=== Other Diagnostic Studies === | === Other Diagnostic Studies === | ||
{| style="background:silver; color:black" | {| style="background:silver; color:black" | ||
|- | |- | ||
| Type | | Type | ||
| pH | | pH | ||
Line 317: | Line 320: | ||
| present | | present | ||
| motile, flagellated | | motile, flagellated | ||
|- style="background:silver; color:black" | |- style="background:silver; color:black" | ||
| BV | | BV | ||
| >4.5 | | >4.5 | ||
Line 323: | Line 326: | ||
| fishy | | fishy | ||
| clue cells | | clue cells | ||
|- style="background:silver; color:black" | |- style="background:silver; color:black" | ||
| Candida | | Candida | ||
| <4.5 | | <4.5 | ||
Line 331: | Line 334: | ||
|- style="background:silver; color:black" | |- style="background:silver; color:black" | ||
| GC | | GC | ||
| | | | ||
| mucopurulent | | mucopurulent | ||
| varies | | varies | ||
Line 337: | Line 340: | ||
|- style="background:silver; color:black" | |- style="background:silver; color:black" | ||
| A.V. | | A.V. | ||
| | | | ||
| thin,gray,watery | | thin,gray,watery | ||
| none | | none | ||
Line 347: | Line 350: | ||
'''See most recent CDC guidelines for all STD's''' | '''See most recent CDC guidelines for all STD's''' | ||
=== Acute Pharmacotherapies === | === Acute Pharmacotherapies === | ||
====Bacterial Vaginosis==== | ==== Bacterial Vaginosis ==== | ||
*[[Metronidazole]] single dose for 7 days | * [[Metronidazole]] single dose for 7 days | ||
====[[Candida]] and [[Chlamydia]]==== | ==== [[Candida]] and [[Chlamydia]] ==== | ||
*[[Azithromycin]] | * [[Azithromycin]] | ||
*[[doxycycline]] | * [[doxycycline]] | ||
====Gonorrhea==== | ==== Gonorrhea ==== | ||
* Oral [[ciprofloxacin]] or IM [[ceftriaxone]] | |||
*[[Metronidazole]] single dose for 7 days | ==== Trichomonas ==== | ||
*Intravaginal [[clotrimazole]] if pregnant or unable to use [[Metronidazole]] | |||
* [[Metronidazole]] single dose for 7 days | |||
* Intravaginal [[clotrimazole]] if pregnant or unable to use [[Metronidazole]] | |||
== References == | == References == | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{Symptoms and signs}} | {{Symptoms and signs}} | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Revision as of 23:16, 23 August 2012
For patient information, click here
Vaginal discharge | |
MedlinePlus | 003158 |
---|
WikiDoc Resources for Vaginal discharge |
Articles |
---|
Most recent articles on Vaginal discharge Most cited articles on Vaginal discharge |
Media |
Powerpoint slides on Vaginal discharge |
Evidence Based Medicine |
Cochrane Collaboration on Vaginal discharge |
Clinical Trials |
Ongoing Trials on Vaginal discharge at Clinical Trials.gov Trial results on Vaginal discharge Clinical Trials on Vaginal discharge at Google
|
Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Vaginal discharge NICE Guidance on Vaginal discharge
|
Books |
News |
Commentary |
Definitions |
Patient Resources / Community |
Patient resources on Vaginal discharge Discussion groups on Vaginal discharge Patient Handouts on Vaginal discharge Directions to Hospitals Treating Vaginal discharge Risk calculators and risk factors for Vaginal discharge
|
Healthcare Provider Resources |
Causes & Risk Factors for Vaginal discharge |
Continuing Medical Education (CME) |
International |
|
Business |
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shankar Kumar, M.B.B.S. [2]]
Overview
Vaginal discharge is a common patient complaint that is paired with anxiety regarding sexually transmitted diseases. If a STD is detected, a search for all other STDs should be done. Advise the infected patient to inform all sexual partners of their diagnosis.
Common causes of Vaginal discharge
Complete Differential Diagnosis of the Causes of Vaginal discharge
(By organ system)
Complete Differential Diagnosis of the Causes of Vaginal discharge
(In alphabetical order)
Laboratory Findings
Initial tests include:
Other Diagnostic Studies
Type | pH | Discharge | Odor | Wet Mount |
Trich | >4.5 | yellow-green, copious | present | motile, flagellated |
BV | >4.5 | white-grey | fishy | clue cells |
Candida | <4.5 | white, curd-like | none | pseudo-hyphae |
GC | mucopurulent | varies | PMNs | |
A.V. | thin,gray,watery | none | few epithelial cells |
Treatment
See most recent CDC guidelines for all STD's
Acute Pharmacotherapies
Bacterial Vaginosis
- Metronidazole single dose for 7 days
Candida and Chlamydia
Gonorrhea
- Oral ciprofloxacin or IM ceftriaxone
Trichomonas
- Metronidazole single dose for 7 days
- Intravaginal clotrimazole if pregnant or unable to use Metronidazole
References
Template:Skin and subcutaneous tissue symptoms and signs Template:Nervous and musculoskeletal system symptoms and signs Template:Urinary system symptoms and signs Template:Cognition, perception, emotional state and behaviour symptoms and signs Template:Speech and voice symptoms and signs Template:General symptoms and signs