Rheumatoid arthritis natural history

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Complications

Rheumatological

• Joint deformitites
• Felty's syndrome
• Sjögren's syndrome

Cardiac complications

• Pericarditis
• Congestive heart failure
• Endocarditis
• Myocardial infarction

Pulmonary complications

• Pleurisy,
• Alveolitis,
• Pulmonary effusion
• Pulmonary fibrosis

Eye complications

• Scleritis, and
• Subcutaneous nodules

Renal complications

• Chronic renal failure from amyloidosis

Nervous system complications

• Peripheral neuropathy and mononeuritis multiplex
• Quadriplegia

Orthopedic complications

• Erosion of the odontoid process and or/transverse ligaments in the cervical spine
• Osteoporosis
• Atlanto-axial subluxation

Hematological complications

• Lymphoma
• Anemia