Henoch-Schönlein purpura other diagnostic studies: Difference between revisions
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==Skin biopsy== | ==Skin biopsy== | ||
If there is doubt about the cause of the skin lesions, a [[biopsy]] of the skin may be performed to distinguish the purpura from other diseases that cause purpura (such as [[vasculitis]] due to [[cryoglobulinemia]]); on microscopy the appearances are of a[[hypersensitivity vasculitis]] and [[immunofluorescence]] demonstrates IgA and [[C3 (complement)|C3]] (a protein of the[[complement system]]) in the blood vessel wall. | If there is doubt about the cause of the skin lesions, a [[biopsy]] of the skin may be performed to distinguish the purpura from other diseases that cause purpura (such as [[vasculitis]] due to [[cryoglobulinemia]]); on microscopy the appearances are of a [[hypersensitivity vasculitis]] and [[immunofluorescence]] demonstrates IgA and [[C3 (complement)|C3]] (a protein of the [[complement system]]) in the blood vessel wall. | ||
==References== | ==References== | ||
Revision as of 17:49, 23 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Skin biopsy
If there is doubt about the cause of the skin lesions, a biopsy of the skin may be performed to distinguish the purpura from other diseases that cause purpura (such as vasculitis due to cryoglobulinemia); on microscopy the appearances are of a hypersensitivity vasculitis and immunofluorescence demonstrates IgA and C3 (a protein of the complement system) in the blood vessel wall.