Cushing's syndrome differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Differentiating Cushing's syndrome from Other Diseases

Causes Suggestive findings Diagnostic approach Skin infections Bacterial Skin edema, erythema, and warmth. Pruritus, pain, and discharge from the lesions. Physical examination reveals local inflammatory findings Culture/sensitivity of discharge Candidal Erythematous skin plaques and erosions with peripheral scaling. Pruritus on the skin plaques. KOH preparation of skin scrapings Scabies Erythematous papules with hemorrhagic crustings. Pruritus, pain, and bleeding from papules. Identification of eggs on skin scrapings HPV (Condylomata acuminata) Soft papules/plaques in the anogenital area. Pruritus, pain, and bleeding from papules. Physical examination Shave biopsy of the lesion Other skin diseases Atopic dermatitis Scaly, erythematous, pruritic and skin lesions. Physical examination Seborrheic dermatitis Erythematous, yellow, oily plaques Mild pruritus Physical examination Contact dermatitis Erythematous, pruritic skin lesion Physical examination Lichen planus Pruritic, purple, polygonal plaques or papules. Physical examination Punch/shave biopsy Lichen sclerosus Vulvular/anal pruritis and thinning of the skin. Physical examination Punch/shave biopsy Perianal carcinoma (Bowen disease or Paget's disease) Rectal bleeding Perianal pruritus Eczematous plaque Rectal mass Physical examination Sigmoidoscopy/colonoscopy CT/PET scan References Template:WH Template:WS