Bradycardia pathophysiology: Difference between revisions

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There are generally two types of problems that result in bradycardias:
There are generally two types of problems that result in bradycardias:
===Disorders of the [[sinus node]] ===
===Disorders of the [[sinus node]] ===
* Impaired automaticity - Sinus node dysfunction/[[sick sinus syndrome]])
* Impaired automaticity - Sinus node dysfunction/[[sick sinus syndrome]])<ref name="pmid6620520">{{cite journal| author=Alpert MA, Flaker GC| title=Arrhythmias associated with sinus node dysfunction. Pathogenesis, recognition, and management. | journal=JAMA | year= 1983 | volume= 250 | issue= 16 | pages= 2160-6 | pmid=6620520 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6620520  }} </ref>
* Exit block - Impaired conduction of the impulse from the sinus node into the surrounding atrial tissue
* Exit block - Impaired conduction of the impulse from the sinus node into the surrounding atrial tissue
===Disorders of the [[atrioventricular node]] (AV node)===
===Disorders of the [[atrioventricular node]] (AV node)===
*  Atrioventricular conduction disturbances ([[First degree AV block|1<sup>o</sup> AV block]], [[Second degree AV block|2<sup>o</sup> type I AV block]], [[Second degree AV block|2<sup>o</sup> type II AV block]], [[Third degree AV block|3<sup>o</sup> AV block]]) may result from impaired conduction in the AV node, or anywhere below it, such as in the bundle of HIS.
*  Atrioventricular conduction disturbances ([[First degree AV block|1<sup>o</sup> AV block]], [[Second degree AV block|2<sup>o</sup> type I AV block]], [[Second degree AV block|2<sup>o</sup> type II AV block]], [[Third degree AV block|3<sup>o</sup> AV block]]) may result from impaired conduction in the AV node, or anywhere below it, such as in the bundle of HIS.

Revision as of 02:03, 25 August 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M.Umer Tariq [2]

Overview

Pathophysiology

It is difficult and sometimes impossible to assign a mechanism to any particular bradycardia. However, the underlying mechanism is not clinically relevant to treatment, which is the same in both cases of sick sinus syndrome: a permanent pacemaker.

There are generally two types of problems that result in bradycardias:

Disorders of the sinus node

  • Impaired automaticity - Sinus node dysfunction/sick sinus syndrome)[1]
  • Exit block - Impaired conduction of the impulse from the sinus node into the surrounding atrial tissue

Disorders of the atrioventricular node (AV node)

References

  1. Alpert MA, Flaker GC (1983). "Arrhythmias associated with sinus node dysfunction. Pathogenesis, recognition, and management". JAMA. 250 (16): 2160–6. PMID 6620520.

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