Graves' disease other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Other Imaging Findings

Thyroid Scintigraphy

• High RAIU: de novo T4 synthesis

• Toxic adenoma
• Toxic multinodular goiter
• TSH-producing pituitary tumor
• Hcg-secreting tumor
• Hyperemesis gravidarum

• Low RAIU: released or exogenous T4

• Thyroiditis - painful, painless, post-partum
• Amiodarone toxicity
• Factitious hyperthyroidism
• Struma ovarii (rare)
• Metastatic thyroid CA (ridiculously rare)

• Thyroid-stimulating antibodies bind and stimulate the TSH receptor
• Anti-TSHR ABs are 80-95% sensitive, 80-90% specific for Graves’